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Decision-Model Estimation of the Age-Specific Disability Weight for Schistosomiasis Japonica: A Systematic Review of the Literature

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  • Julia L Finkelstein
  • Mark D Schleinitz
  • Hélène Carabin
  • Stephen T McGarvey

Abstract

Schistosomiasis is among the most prevalent parasitic infections worldwide. However, current Global Burden of Disease (GBD) disability-adjusted life year estimates indicate that its population-level impact is negligible. Recent studies suggest that GBD methodologies may significantly underestimate the burden of parasitic diseases, including schistosomiasis. Furthermore, strain-specific disability weights have not been established for schistosomiasis, and the magnitude of human disease burden due to Schistosoma japonicum remains controversial. We used a decision model to quantify an alternative disability weight estimate of the burden of human disease due to S. japonicum. We reviewed S. japonicum morbidity data, and constructed decision trees for all infected persons and two age-specific strata,

Suggested Citation

  • Julia L Finkelstein & Mark D Schleinitz & Hélène Carabin & Stephen T McGarvey, 2008. "Decision-Model Estimation of the Age-Specific Disability Weight for Schistosomiasis Japonica: A Systematic Review of the Literature," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 2(3), pages 1-10, March.
    • Handle: RePEc:plo:pntd00:0000158
    DOI: 10.1371/journal.pntd.0000158
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