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Challenges in interpreting cytokine data in COVID-19 affect patient care and management

Author

Listed:
  • Stephen Y Wang
  • Takehiro Takahashi
  • Alexander B Pine
  • William E Damsky
  • Michael Simonov
  • Yanhua Zhang
  • Elizabeth Kieras
  • Christina C Price
  • Brett A King
  • Mark D Siegel
  • Gary V Desir
  • Alfred I Lee
  • Akiko Iwasaki
  • Hyung J Chun

Abstract

Challenges in using cytokine data are limiting Coronavirus Disease 2019 (COVID-19) patient management and comparison among different disease contexts. We suggest mitigation strategies to improve the accuracy of cytokine data, as we learn from experience gained during the COVID-19 pandemic.The importance of cytokine storms in COVID-19 continues to be widely debated. This Perspective article discusses the challenges in using cytokine measurement in COVID-19 and other disease states as we strive to improve our understanding and treatment of COVID-19.

Suggested Citation

  • Stephen Y Wang & Takehiro Takahashi & Alexander B Pine & William E Damsky & Michael Simonov & Yanhua Zhang & Elizabeth Kieras & Christina C Price & Brett A King & Mark D Siegel & Gary V Desir & Alfred, 2021. "Challenges in interpreting cytokine data in COVID-19 affect patient care and management," PLOS Biology, Public Library of Science, vol. 19(8), pages 1-5, August.
    • Handle: RePEc:plo:pbio00:3001373
    DOI: 10.1371/journal.pbio.3001373
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