IDEAS home Printed from https://ideas.repec.org/a/oup/geronb/v78y2023i10p1651-1658..html
   My bibliography  Save this article

Functional Connectivity Alterations of Cognitive Flexibility in Aging: Different Patterns of Global and Local Switch Costs

Author

Listed:
  • Ting Li
  • Haishuo Xia
  • Huai Li
  • Qinghua He
  • Antao Chen
  • Anne Krendl

Abstract

ObjectivesCognitive flexibility declines with aging and is usually indicated by task switch costs including global and local switch costs. Cognitive flexibility in aging is associated with alterations in functional connectivity. However, whether different task-modulated connectivity mechanisms underlying global and local switch costs remain unclear.MethodsHere we use the support vector machine to identify age-related functional connectivity in global and local switch costs between older (n = 32) and young adults (n = 33). Participants completed a cued task-switching task during the functional magnetic resonance imaging scan.ResultsResults show an age-related decline behaviorally in global but not in local switch costs. Moreover, distinct patterns of age-related alterations of connectivity were observed for each cost. Specifically, only multivariate changes in connectivity patterns were observed for local switch cost, whereas specific age-related connections were revealed for global switch cost. In older adults, the task-modulated left dorsal premotor cortex–left precuneus connectivity decreased, and the left inferior frontal junction–left inferior parietal sulcus connectivity correlated with decreased global switch cost.DiscussionThis study provides novel evidence for different neural patterns in global and local switch costs by illuminating connectivity mechanisms underlying cognitive flexibility in aging.

Suggested Citation

  • Ting Li & Haishuo Xia & Huai Li & Qinghua He & Antao Chen & Anne Krendl, 2023. "Functional Connectivity Alterations of Cognitive Flexibility in Aging: Different Patterns of Global and Local Switch Costs," The Journals of Gerontology: Series B, The Gerontological Society of America, vol. 78(10), pages 1651-1658.
    • Handle: RePEc:oup:geronb:v:78:y:2023:i:10:p:1651-1658.
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.1093/geronb/gbad092
    Download Restriction: Access to full text is restricted to subscribers.
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:oup:geronb:v:78:y:2023:i:10:p:1651-1658.. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Oxford University Press (email available below). General contact details of provider: https://academic.oup.com/psychsocgerontology .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.