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Fertility History and Risk of Cognitive Impairment Among Older Parents in the United States
[Diabetes, Alzheimer disease, and vascular dementia: A population-based neuropathologic study]

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  • Yan Zhang
  • Jessica Kelley

Abstract

ObjectivesI work from a gendered life-course perspective to examine the association between older parents’ fertility history (i.e., timing and parity) and their risk of cognitive impairment in the United States.MethodsI analyze nationally representative data from 9 waves over 16 years of the Health and Retirement Study (2000–2016). The sample includes 14,543 respondents (6,108 men and 8,435 women) aged 50 and older at the baseline survey. I examine the relationship between parity, age at first birth, and age at last birth with risk of cognitive impairment using nonlinear discrete-time hazard models.ResultsAdjusting for the effects of full covariates, there are U-shaped relationships between women’s age at last birth and risk of cognitive impairment and between women’s parity and risk of cognitive impairment. In the sensitivity tests, the relationships remain robust when sampling weights are applied, or mortality selection is corrected.DiscussionFertility timing and parity are likely factors associated with the risk of cognitive impairment for older women. Understanding fertility history and its impact on cognition can help identify the most vulnerable subpopulations, so that more effective interventions can be made to improve cognitive functioning among older adults.

Suggested Citation

  • Yan Zhang & Jessica Kelley, 2022. "Fertility History and Risk of Cognitive Impairment Among Older Parents in the United States [Diabetes, Alzheimer disease, and vascular dementia: A population-based neuropathologic study]," The Journals of Gerontology: Series B, The Gerontological Society of America, vol. 77(12), pages 2326-2337.
    • Handle: RePEc:oup:geronb:v:77:y:2022:i:12:p:2326-2337.
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    File URL: http://hdl.handle.net/10.1093/geronb/gbac091
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    Cited by:

    1. Zhang, Yan & Fletcher, Jason & Lu, Qiongshi & Song, Jie, 2023. "Gender differences in the association between parity and cognitive function: Evidence from the UK biobank," Social Science & Medicine, Elsevier, vol. 320(C).

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