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How the cGAS–STING system links inflammation and cognitive decline

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  • Bart J. L. Eggen

Abstract

When DNA is misplaced inside cells, the cGAS–STING molecular system triggers inflammation. It emerges that stimulation of this mechanism in microglial cells of the brain during ageing contributes to cognitive decline.

Suggested Citation

  • Bart J. L. Eggen, 2023. "How the cGAS–STING system links inflammation and cognitive decline," Nature, Nature, vol. 620(7973), pages 280-282, August.
    • Handle: RePEc:nat:nature:v:620:y:2023:i:7973:d:10.1038_d41586-023-02240-1
    DOI: 10.1038/d41586-023-02240-1
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