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An open science study of ageing in companion dogs

Author

Listed:
  • Kate E. Creevy

    (Texas A&M University College of Veterinary Medicine & Biomedical Sciences)

  • Joshua M. Akey

    (Princeton University)

  • Matt Kaeberlein

    (University of Washington School of Medicine)

  • Daniel E. L. Promislow

    (University of Washington School of Medicine
    University of Washington)

Abstract

The Dog Aging Project is a long-term longitudinal study of ageing in tens of thousands of companion dogs. The domestic dog is among the most variable mammal species in terms of morphology, behaviour, risk of age-related disease and life expectancy. Given that dogs share the human environment and have a sophisticated healthcare system but are much shorter-lived than people, they offer a unique opportunity to identify the genetic, environmental and lifestyle factors associated with healthy lifespan. To take advantage of this opportunity, the Dog Aging Project will collect extensive survey data, environmental information, electronic veterinary medical records, genome-wide sequence information, clinicopathology and molecular phenotypes derived from blood cells, plasma and faecal samples. Here, we describe the specific goals and design of the Dog Aging Project and discuss the potential for this open-data, community science study to greatly enhance understanding of ageing in a genetically variable, socially relevant species living in a complex environment.

Suggested Citation

  • Kate E. Creevy & Joshua M. Akey & Matt Kaeberlein & Daniel E. L. Promislow, 2022. "An open science study of ageing in companion dogs," Nature, Nature, vol. 602(7895), pages 51-57, February.
    • Handle: RePEc:nat:nature:v:602:y:2022:i:7895:d:10.1038_s41586-021-04282-9
    DOI: 10.1038/s41586-021-04282-9
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    Cited by:

    1. Anufriyeva, Valentyna & Pavlova, Milena & Chernysh (Stepurko), Tetiana & Groot, Wim, 2023. "Satisfaction with primary health care in Ukraine in 2016–2020: A difference-in-differences analysis on repeated cross-sectional data," Health Policy, Elsevier, vol. 137(C).
    2. Treiblmaier, Horst & Petrozhitskaya, Elena, 2023. "Is it time for marketing to reappraise B2C relationship management? The emergence of a new loyalty paradigm through blockchain technology," Journal of Business Research, Elsevier, vol. 159(C).

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