Cancer SLC43A2 alters T cell methionine metabolism and histone methylation
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DOI: 10.1038/s41586-020-2682-1
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- Le Tran Phuc Khoa & Wentao Yang & Mengrou Shan & Li Zhang & Fengbiao Mao & Bo Zhou & Qiang Li & Rebecca Malcore & Clair Harris & Lili Zhao & Rajesh C. Rao & Shigeki Iwase & Sundeep Kalantry & Stephani, 2024. "Quiescence enables unrestricted cell fate in naive embryonic stem cells," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
- Ying Huang & Geng Qin & TingTing Cui & Chuanqi Zhao & Jinsong Ren & Xiaogang Qu, 2023. "A bimetallic nanoplatform for STING activation and CRISPR/Cas mediated depletion of the methionine transporter in cancer cells restores anti-tumor immune responses," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Zenan Wang & Binghao Li & Shan Li & Wenlong Lin & Zhan Wang & Shengdong Wang & Weida Chen & Wei Shi & Tao Chen & Hao Zhou & Eloy Yinwang & Wenkan Zhang & Haochen Mou & Xupeng Chai & Jiahao Zhang & Zhi, 2022. "Metabolic control of CD47 expression through LAT2-mediated amino acid uptake promotes tumor immune evasion," Nature Communications, Nature, vol. 13(1), pages 1-19, December.
- Mahesh Pandit & Yun-Seo Kil & Jae-Hee Ahn & Ram Hari Pokhrel & Ye Gu & Sunil Mishra & Youngjoo Han & Yung-Taek Ouh & Ben Kang & Myeong Seon Jeong & Jong-Oh Kim & Joo-Won Nam & Hyun-Jeong Ko & Jae-Hoon, 2023. "Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Wenfeng Ren & Zilong Xu & Yating Chang & Fei Ju & Hongning Wu & Zhiqi Liang & Min Zhao & Naizhen Wang & Yanhua Lin & Chenhang Xu & Shengming Chen & Yipeng Rao & Chaolong Lin & Jianxin Yang & Pingguo L, 2024. "Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Hanhan Ning & Shan Huang & Yang Lei & Renyong Zhi & Han Yan & Jiaxing Jin & Zhenyu Hu & Kaimin Guo & Jinhua Liu & Jie Yang & Zhe Liu & Yi Ba & Xin Gao & Deqing Hu, 2022. "Enhancer decommissioning by MLL4 ablation elicits dsRNA-interferon signaling and GSDMD-mediated pyroptosis to potentiate anti-tumor immunity," Nature Communications, Nature, vol. 13(1), pages 1-20, December.
- Chunge Zhong & Wen-Jie Jiang & Yingjia Yao & Zexu Li & You Li & Shengnan Wang & Xiaofeng Wang & Wenjuan Zhu & Siqi Wu & Jing Wang & Shuangshuang Fan & Shixin Ma & Yeshu Liu & Han Zhang & Wenchang Zhao, 2024. "CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer," Nature Communications, Nature, vol. 15(1), pages 1-21, December.
- Ying Xue & Fujia Lu & Zhenzhen Chang & Jing Li & Yuan Gao & Jie Zhou & Ying Luo & Yongfeng Lai & Siyuan Cao & Xiaoxiao Li & Yuhan Zhou & Yan Li & Zheng Tan & Xiang Cheng & Xiong Li & Jing Chen & Weimi, 2023. "Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
- Wen Fang & Liu Jiang & Yibing Zhu & Sen Yang & Hong Qiu & Jiou Cheng & Qingxi Liang & Zong-cai Tu & Cunqi Ye, 2023. "Methionine restriction constrains lipoylation and activates mitochondria for nitrogenic synthesis of amino acids," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
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