In vivo CRISPR editing with no detectable genome-wide off-target mutations
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DOI: 10.1038/s41586-018-0500-9
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Cited by:
- Zhenxing Yu & Zhike Lu & Jingjing Li & Yingying Wang & Panfeng Wu & Yini Li & Yangfan Zhou & Bailun Li & Heng Zhang & Yingzheng Liu & Lijia Ma, 2022. "PEAC-seq adopts Prime Editor to detect CRISPR off-target and DNA translocation," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
- Burcu Bestas & Sandra Wimberger & Dmitrii Degtev & Alexandra Madsen & Antje K. Rottner & Fredrik Karlsson & Sergey Naumenko & Megan Callahan & Julia Liz Touza & Margherita Francescatto & Carl Ivar Möl, 2023. "A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Gernot Neumayer & Jessica L. Torkelson & Shengdi Li & Kelly McCarthy & Hanson H. Zhen & Madhuri Vangipuram & Marius M. Mader & Gulilat Gebeyehu & Taysir M. Jaouni & Joanna Jacków-Malinowska & Avina Ra, 2024. "A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
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Keywords
Gene-editing Nucleases; CRISPR-Cas9 Nuclease; Targeted Amplicon Sequencing; Supplementary Discussion; PCSK9 Gene;All these keywords.
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