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The protein histidine phosphatase LHPP is a tumour suppressor

Author

Listed:
  • Sravanth K. Hindupur

    (Biozentrum, University of Basel)

  • Marco Colombi

    (Biozentrum, University of Basel)

  • Stephen R. Fuhs

    (Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies)

  • Matthias S. Matter

    (Institute of Pathology, University Hospital Basel)

  • Yakir Guri

    (Biozentrum, University of Basel)

  • Kevin Adam

    (Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies)

  • Marion Cornu

    (Biozentrum, University of Basel)

  • Salvatore Piscuoglio

    (Institute of Pathology, University Hospital Basel)

  • Charlotte K. Y. Ng

    (Institute of Pathology, University Hospital Basel)

  • Charles Betz

    (Biozentrum, University of Basel)

  • Dritan Liko

    (Biozentrum, University of Basel)

  • Luca Quagliata

    (Institute of Pathology, University Hospital Basel)

  • Suzette Moes

    (Biozentrum, University of Basel)

  • Paul Jenoe

    (Biozentrum, University of Basel)

  • Luigi M. Terracciano

    (Institute of Pathology, University Hospital Basel)

  • Markus H. Heim

    (University Hospital Basel)

  • Tony Hunter

    (Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies)

  • Michael N. Hall

    (Biozentrum, University of Basel)

Abstract

Decreased expression of histidine phosphatase LHPP, a novel tumour suppressor, results in increased global histidine phosphorylation and hepatocellular carcinoma.

Suggested Citation

  • Sravanth K. Hindupur & Marco Colombi & Stephen R. Fuhs & Matthias S. Matter & Yakir Guri & Kevin Adam & Marion Cornu & Salvatore Piscuoglio & Charlotte K. Y. Ng & Charles Betz & Dritan Liko & Luca Qua, 2018. "The protein histidine phosphatase LHPP is a tumour suppressor," Nature, Nature, vol. 555(7698), pages 678-682, March.
  • Handle: RePEc:nat:nature:v:555:y:2018:i:7698:d:10.1038_nature26140
    DOI: 10.1038/nature26140
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