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Dysregulation of expression correlates with rare-allele burden and fitness loss in maize

Author

Listed:
  • Karl A. G. Kremling

    (Section of Plant Breeding and Genetics, 175 Biotechnology Building, Cornell University)

  • Shu-Yun Chen

    (Institute for Genomic Diversity, 175 Biotechnology Building, Cornell University
    Institute of Plant and Microbial Biology)

  • Mei-Hsiu Su

    (Institute for Genomic Diversity, 175 Biotechnology Building, Cornell University)

  • Nicholas K. Lepak

    (USDA-ARS, R. W. Holley Center, Cornell University)

  • M. Cinta Romay

    (Institute for Genomic Diversity, 175 Biotechnology Building, Cornell University)

  • Kelly L. Swarts

    (Section of Plant Breeding and Genetics, 175 Biotechnology Building, Cornell University
    Research Group for Ancient Genomics and Evolution, Max Planck Institute for Developmental Biology)

  • Fei Lu

    (Institute for Genomic Diversity, 175 Biotechnology Building, Cornell University
    The State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences)

  • Anne Lorant

    (University of California Davis)

  • Peter J. Bradbury

    (USDA-ARS, R. W. Holley Center, Cornell University)

  • Edward S. Buckler

    (Section of Plant Breeding and Genetics, 175 Biotechnology Building, Cornell University
    Institute for Genomic Diversity, 175 Biotechnology Building, Cornell University
    USDA-ARS, R. W. Holley Center, Cornell University)

Abstract

A multi-tissue gene expression resource representative of the genotypic and phenotypic diversity of modern inbred maize reveals the effect of rare alleles and evolutionary history on the regulation of gene expression.

Suggested Citation

  • Karl A. G. Kremling & Shu-Yun Chen & Mei-Hsiu Su & Nicholas K. Lepak & M. Cinta Romay & Kelly L. Swarts & Fei Lu & Anne Lorant & Peter J. Bradbury & Edward S. Buckler, 2018. "Dysregulation of expression correlates with rare-allele burden and fitness loss in maize," Nature, Nature, vol. 555(7697), pages 520-523, March.
    • Handle: RePEc:nat:nature:v:555:y:2018:i:7697:d:10.1038_nature25966
    DOI: 10.1038/nature25966
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