IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v554y2018i7691d10.1038_nature25481.html
   My bibliography  Save this article

Dynamics and number of trans-SNARE complexes determine nascent fusion pore properties

Author

Listed:
  • Huan Bao

    (University of Wisconsin–Madison
    Howard Hughes Medical Institute)

  • Debasis Das

    (University of Wisconsin–Madison
    Howard Hughes Medical Institute)

  • Nicholas A. Courtney

    (University of Wisconsin–Madison
    Howard Hughes Medical Institute)

  • Yihao Jiang

    (University of Wisconsin–Madison)

  • Joseph S. Briguglio

    (University of Wisconsin–Madison
    Howard Hughes Medical Institute)

  • Xiaochu Lou

    (University of Wisconsin–Madison
    Howard Hughes Medical Institute)

  • Daniel Roston

    (University of Wisconsin)

  • Qiang Cui

    (University of Wisconsin)

  • Baron Chanda

    (University of Wisconsin–Madison
    University of Wisconsin)

  • Edwin R. Chapman

    (University of Wisconsin–Madison
    Howard Hughes Medical Institute)

Abstract

Analysis at high temporal and spatial resolution shows that the number and dynamics of SNARE proteins available during exocytosis determines the size and stability of fusion pores.

Suggested Citation

  • Huan Bao & Debasis Das & Nicholas A. Courtney & Yihao Jiang & Joseph S. Briguglio & Xiaochu Lou & Daniel Roston & Qiang Cui & Baron Chanda & Edwin R. Chapman, 2018. "Dynamics and number of trans-SNARE complexes determine nascent fusion pore properties," Nature, Nature, vol. 554(7691), pages 260-263, February.
    • Handle: RePEc:nat:nature:v:554:y:2018:i:7691:d:10.1038_nature25481
    DOI: 10.1038/nature25481
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature25481
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature25481?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Kevin C. Courtney & Taraknath Mandal & Nikunj Mehta & Lanxi Wu & Yueqi Li & Debasis Das & Qiang Cui & Edwin R. Chapman, 2023. "Synaptotagmin-7 outperforms synaptotagmin-1 to promote the formation of large, stable fusion pores via robust membrane penetration," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    2. Ling-Gang Wu & Chung Yu Chan, 2024. "Membrane transformations of fusion and budding," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
    3. Bhavya R. Bhaskar & Laxmi Yadav & Malavika Sriram & Kinjal Sanghrajka & Mayank Gupta & Boby K. V & Rohith K. Nellikka & Debasis Das, 2024. "Differential SNARE chaperoning by Munc13-1 and Munc18-1 dictates fusion pore fate at the release site," Nature Communications, Nature, vol. 15(1), pages 1-18, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:554:y:2018:i:7691:d:10.1038_nature25481. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.