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Precision editing of the gut microbiota ameliorates colitis

Author

Listed:
  • Wenhan Zhu

    (University of Texas Southwestern Medical Center)

  • Maria G. Winter

    (University of Texas Southwestern Medical Center)

  • Mariana X. Byndloss

    (School of Medicine, University of California, Davis, One Shields Avenue)

  • Luisella Spiga

    (University of Texas Southwestern Medical Center)

  • Breck A. Duerkop

    (University of Texas Southwestern Medical Center)

  • Elizabeth R. Hughes

    (University of Texas Southwestern Medical Center)

  • Lisa Büttner

    (University of Texas Southwestern Medical Center)

  • Everton de Lima Romão

    (School of Medicine, University of California, Davis, One Shields Avenue)

  • Cassie L. Behrendt

    (University of Texas Southwestern Medical Center)

  • Christopher A. Lopez

    (School of Medicine, University of California, Davis, One Shields Avenue)

  • Luis Sifuentes-Dominguez

    (University of Texas Southwestern Medical Center)

  • Kayci Huff-Hardy

    (University of Texas Southwestern Medical Center 75390)

  • R. Paul Wilson

    (Lewis Katz School of Medicine, Temple University
    GlaxoSmithKline)

  • Caroline C. Gillis

    (University of Texas Southwestern Medical Center)

  • Çagla Tükel

    (Lewis Katz School of Medicine, Temple University)

  • Andrew Y. Koh

    (University of Texas Southwestern Medical Center
    University of Texas Southwestern Medical Center)

  • Ezra Burstein

    (University of Texas Southwestern Medical Center 75390)

  • Lora V. Hooper

    (University of Texas Southwestern Medical Center
    Howard Hughes Medical Institute, University of Texas Southwestern Medical Center)

  • Andreas J. Bäumler

    (School of Medicine, University of California, Davis, One Shields Avenue)

  • Sebastian E. Winter

    (University of Texas Southwestern Medical Center)

Abstract

Tungstate inhibits molybdenum-cofactor-dependent microbial respiratory pathways and shows potential as a selective treatment for microbial imbalances that occur during inflammation of the gastrointestinal tract.

Suggested Citation

  • Wenhan Zhu & Maria G. Winter & Mariana X. Byndloss & Luisella Spiga & Breck A. Duerkop & Elizabeth R. Hughes & Lisa Büttner & Everton de Lima Romão & Cassie L. Behrendt & Christopher A. Lopez & Luis S, 2018. "Precision editing of the gut microbiota ameliorates colitis," Nature, Nature, vol. 553(7687), pages 208-211, January.
    • Handle: RePEc:nat:nature:v:553:y:2018:i:7687:d:10.1038_nature25172
    DOI: 10.1038/nature25172
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