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Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host

Author

Listed:
  • David Palesch

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University)

  • Steven E. Bosinger

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
    Emory University School of Medicine)

  • Gregory K. Tharp

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University)

  • Thomas H. Vanderford

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University)

  • Mirko Paiardini

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
    Emory University School of Medicine)

  • Ann Chahroudi

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
    Emory University School of Medicine)

  • Zachary P. Johnson

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University)

  • Frank Kirchhoff

    (Institute of Molecular Virology, Ulm University Medical Center)

  • Beatrice H. Hahn

    (Perelman School of Medicine, University of Pennsylvania)

  • Robert B. Norgren

    (Cell Biology and Anatomy, University of Nebraska, Medical Center)

  • Nirav B. Patel

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University)

  • Donald L. Sodora

    (Center for Infectious Disease Research, formerly Seattle Biomedical Research Institute, Seattle)

  • Reem A. Dawoud

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University)

  • Caro-Beth Stewart

    (University at Albany-State University of New York)

  • Sara M. Seepo

    (University at Albany-State University of New York)

  • R. Alan Harris

    (Human Genome Sequencing Center, Baylor College of Medicine
    Baylor College of Medicine)

  • Yue Liu

    (Human Genome Sequencing Center, Baylor College of Medicine)

  • Muthuswamy Raveendran

    (Human Genome Sequencing Center, Baylor College of Medicine
    Baylor College of Medicine)

  • Yi Han

    (Human Genome Sequencing Center, Baylor College of Medicine)

  • Adam English

    (Human Genome Sequencing Center, Baylor College of Medicine)

  • Gregg W. C. Thomas

    (Indiana University)

  • Matthew W. Hahn

    (Indiana University)

  • Lenore Pipes

    (Weill Cornell Medical College)

  • Christopher E. Mason

    (Weill Cornell Medical College)

  • Donna M. Muzny

    (Human Genome Sequencing Center, Baylor College of Medicine
    Baylor College of Medicine)

  • Richard A. Gibbs

    (Human Genome Sequencing Center, Baylor College of Medicine
    Baylor College of Medicine)

  • Daniel Sauter

    (Institute of Molecular Virology, Ulm University Medical Center)

  • Kim Worley

    (Human Genome Sequencing Center, Baylor College of Medicine
    Baylor College of Medicine)

  • Jeffrey Rogers

    (Human Genome Sequencing Center, Baylor College of Medicine
    Baylor College of Medicine)

  • Guido Silvestri

    (Emory Vaccine Center and Yerkes National Primate Research Center, Emory University
    Emory University School of Medicine)

Abstract

Whole-genome sequencing and comparative genomic analysis of immune-related genes of Cercocebus atys and Macaca mulatta identify candidate genes, such as ICAM2 and TLR4, that may explain the AIDS resistance of C. atys.

Suggested Citation

  • David Palesch & Steven E. Bosinger & Gregory K. Tharp & Thomas H. Vanderford & Mirko Paiardini & Ann Chahroudi & Zachary P. Johnson & Frank Kirchhoff & Beatrice H. Hahn & Robert B. Norgren & Nirav B. , 2018. "Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host," Nature, Nature, vol. 553(7686), pages 77-81, January.
    • Handle: RePEc:nat:nature:v:553:y:2018:i:7686:d:10.1038_nature25140
    DOI: 10.1038/nature25140
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