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Establishment of mouse expanded potential stem cells

Author

Listed:
  • Jian Yang

    (Wellcome Trust Sanger Institute)

  • David J. Ryan

    (Wellcome Trust Sanger Institute)

  • Wei Wang

    (Wellcome Trust Sanger Institute)

  • Jason Cheuk-Ho Tsang

    (Wellcome Trust Sanger Institute)

  • Guocheng Lan

    (Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre)

  • Hideki Masaki

    (Institute of Medical Science, University of Tokyo)

  • Xuefei Gao

    (Wellcome Trust Sanger Institute)

  • Liliana Antunes

    (Wellcome Trust Sanger Institute)

  • Yong Yu

    (Wellcome Trust Sanger Institute)

  • Zhexin Zhu

    (Wellcome Trust Sanger Institute)

  • Juexuan Wang

    (Wellcome Trust Sanger Institute)

  • Aleksandra A. Kolodziejczyk

    (Wellcome Trust Sanger Institute
    European Molecular Biology Laboratory, European Bioinformatics Institute)

  • Lia S. Campos

    (Wellcome Trust Sanger Institute)

  • Cui Wang

    (Wellcome Trust Sanger Institute)

  • Fengtang Yang

    (Wellcome Trust Sanger Institute)

  • Zhen Zhong

    (Medical Research Council Laboratory of Molecular Biology)

  • Beiyuan Fu

    (Wellcome Trust Sanger Institute)

  • Melanie A. Eckersley-Maslin

    (Epigenetics Programme, The Babraham Institute)

  • Michael Woods

    (Wellcome Trust Sanger Institute)

  • Yosuke Tanaka

    (Cambridge Institute for Medical Research, University of Cambridge
    Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge
    Institute of Medical Science, University of Tokyo)

  • Xi Chen

    (Wellcome Trust Sanger Institute)

  • Adam C. Wilkinson

    (Cambridge Institute for Medical Research, University of Cambridge
    Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge)

  • James Bussell

    (Wellcome Trust Sanger Institute)

  • Jacqui White

    (Wellcome Trust Sanger Institute)

  • Ramiro Ramirez-Solis

    (Wellcome Trust Sanger Institute)

  • Wolf Reik

    (Wellcome Trust Sanger Institute
    Epigenetics Programme, The Babraham Institute)

  • Berthold Göttgens

    (Cambridge Institute for Medical Research, University of Cambridge
    Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge)

  • Sarah A. Teichmann

    (Wellcome Trust Sanger Institute
    European Molecular Biology Laboratory, European Bioinformatics Institute)

  • Patrick P. L. Tam

    (Embryology Unit, Children’s Medical Research Institute, University of Sydney
    School of Medical Sciences, Sydney Medical School, University of Sydney)

  • Hiromitsu Nakauchi

    (Institute of Medical Science, University of Tokyo
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine)

  • Xiangang Zou

    (Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre)

  • Liming Lu

    (Wellcome Trust Sanger Institute
    Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine)

  • Pentao Liu

    (Wellcome Trust Sanger Institute)

Abstract

Cultures of expanded potential stem cells can be established from individual eight-cell blastomeres, and by direct conversion of mouse embryonic stem cells and induced pluripotent stem cells, highlighting the feasibility of establishing expanded potential stem cells for other mammalian species.

Suggested Citation

  • Jian Yang & David J. Ryan & Wei Wang & Jason Cheuk-Ho Tsang & Guocheng Lan & Hideki Masaki & Xuefei Gao & Liliana Antunes & Yong Yu & Zhexin Zhu & Juexuan Wang & Aleksandra A. Kolodziejczyk & Lia S. C, 2017. "Establishment of mouse expanded potential stem cells," Nature, Nature, vol. 550(7676), pages 393-397, October.
    • Handle: RePEc:nat:nature:v:550:y:2017:i:7676:d:10.1038_nature24052
    DOI: 10.1038/nature24052
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    Cited by:

    1. Claire Vinel & Gabriel Rosser & Loredana Guglielmi & Myrianni Constantinou & Nicola Pomella & Xinyu Zhang & James R. Boot & Tania A. Jones & Thomas O. Millner & Anaelle A. Dumas & Vardhman Rakyan & Je, 2021. "Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma," Nature Communications, Nature, vol. 12(1), pages 1-20, December.

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