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A viral Sm-class RNA base-pairs with mRNAs and recruits microRNAs to inhibit apoptosis

Author

Listed:
  • Carlos Gorbea

    (University of Utah School of Medicine)

  • Tim Mosbruger

    (Huntsman Cancer Institute, University of Utah School of Medicine)

  • Demián Cazalla

    (University of Utah School of Medicine)

Abstract

Herpesvirus saimiri expresses a small nuclear RNA named HSUR2, with which it recruits two cellular microRNAs to repress specific mRNA targets and thereby inhibit apoptosis in infected T cells.

Suggested Citation

  • Carlos Gorbea & Tim Mosbruger & Demián Cazalla, 2017. "A viral Sm-class RNA base-pairs with mRNAs and recruits microRNAs to inhibit apoptosis," Nature, Nature, vol. 550(7675), pages 275-279, October.
    • Handle: RePEc:nat:nature:v:550:y:2017:i:7675:d:10.1038_nature24034
    DOI: 10.1038/nature24034
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    Cited by:

    1. Luca F. R. Gebert & Mansun Law & Ian J. MacRae, 2021. "A structured RNA motif locks Argonaute2:miR-122 onto the 5’ end of the HCV genome," Nature Communications, Nature, vol. 12(1), pages 1-13, December.

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