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Stereodivergent synthesis with a programmable molecular machine

Author

Listed:
  • Salma Kassem

    (School of Chemistry, University of Manchester)

  • Alan T. L. Lee

    (School of Chemistry, University of Manchester)

  • David A. Leigh

    (School of Chemistry, University of Manchester)

  • Vanesa Marcos

    (School of Chemistry, University of Manchester)

  • Leoni I. Palmer

    (School of Chemistry, University of Manchester)

  • Simone Pisano

    (School of Chemistry, University of Manchester)

Abstract

A molecular machine that can be programmed to position a substrate at one of two directing sites on a molecule, which control the stereochemistry of addition to the substrate, demonstrates complexity, precision and function previously only observed in nature.

Suggested Citation

  • Salma Kassem & Alan T. L. Lee & David A. Leigh & Vanesa Marcos & Leoni I. Palmer & Simone Pisano, 2017. "Stereodivergent synthesis with a programmable molecular machine," Nature, Nature, vol. 549(7672), pages 374-378, September.
  • Handle: RePEc:nat:nature:v:549:y:2017:i:7672:d:10.1038_nature23677
    DOI: 10.1038/nature23677
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    Cited by:

    1. Ran Chen & Ahmad Hammoud & Paméla Aoun & Mayte A. Martínez-Aguirre & Nicolas Vanthuyne & Régina Maruchenko & Patrick Brocorens & Laurent Bouteiller & Matthieu Raynal, 2024. "Switchable supramolecular helices for asymmetric stereodivergent catalysis," Nature Communications, Nature, vol. 15(1), pages 1-11, December.

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