IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v548y2017i7668d10.1038_nature23653.html
   My bibliography  Save this article

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

Author

Listed:
  • Weike Pei

    (German Cancer Research Center)

  • Thorsten B. Feyerabend

    (German Cancer Research Center)

  • Jens Rössler

    (German Cancer Research Center)

  • Xi Wang

    (German Cancer Research Center
    Max Delbrück Center, Scientific Genomics Platforms (BIMSB/BIH))

  • Daniel Postrach

    (German Cancer Research Center)

  • Katrin Busch

    (German Cancer Research Center)

  • Immanuel Rode

    (German Cancer Research Center)

  • Kay Klapproth

    (German Cancer Research Center)

  • Nikolaus Dietlein

    (German Cancer Research Center)

  • Claudia Quedenau

    (Max Delbrück Center, Scientific Genomics Platforms (BIMSB/BIH))

  • Wei Chen

    (Max Delbrück Center, Scientific Genomics Platforms (BIMSB/BIH))

  • Sascha Sauer

    (Max Delbrück Center, Scientific Genomics Platforms (BIMSB/BIH))

  • Stephan Wolf

    (Genomics & Proteomics Core Facilities, German Cancer Research Center)

  • Thomas Höfer

    (German Cancer Research Center
    Bioquant Center, University of Heidelberg)

  • Hans-Reimer Rodewald

    (German Cancer Research Center)

Abstract

An artificial recombination locus, Polylox, that can generate hundreds of thousands of individual barcodes is used to trace the fates of haematopoietic stem cells in mice.

Suggested Citation

  • Weike Pei & Thorsten B. Feyerabend & Jens Rössler & Xi Wang & Daniel Postrach & Katrin Busch & Immanuel Rode & Kay Klapproth & Nikolaus Dietlein & Claudia Quedenau & Wei Chen & Sascha Sauer & Stephan , 2017. "Polylox barcoding reveals haematopoietic stem cell fates realized in vivo," Nature, Nature, vol. 548(7668), pages 456-460, August.
    • Handle: RePEc:nat:nature:v:548:y:2017:i:7668:d:10.1038_nature23653
    DOI: 10.1038/nature23653
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature23653
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature23653?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Mina N. F. Morcos & Congxin Li & Clara M. Munz & Alessandro Greco & Nicole Dressel & Susanne Reinhardt & Katrin Sameith & Andreas Dahl & Nils B. Becker & Axel Roers & Thomas Höfer & Alexander Gerbaule, 2022. "Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    2. Sara Ballouz & Risa Karakida Kawaguchi & Maria T. Pena & Stephan Fischer & Megan Crow & Leon French & Frank M. Knight & Linda B. Adams & Jesse Gillis, 2023. "The transcriptional legacy of developmental stochasticity," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
    3. C. Biben & T. S. Weber & K. S. Potts & J. Choi & D. C. Miles & A. Carmagnac & T. Sargeant & C. A. Graaf & K. A. Fennell & A. Farley & O. J. Stonehouse & M. A. Dawson & D. J. Hilton & S. H. Naik & S. T, 2023. "In vivo clonal tracking reveals evidence of haemangioblast and haematomesoblast contribution to yolk sac haematopoiesis," Nature Communications, Nature, vol. 14(1), pages 1-14, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:548:y:2017:i:7668:d:10.1038_nature23653. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.