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Correction of aberrant growth preserves tissue homeostasis

Author

Listed:
  • Samara Brown

    (Yale School of Medicine)

  • Cristiana M. Pineda

    (Yale School of Medicine)

  • Tianchi Xin

    (Yale School of Medicine)

  • Jonathan Boucher

    (Yale School of Medicine)

  • Kathleen C. Suozzi

    (Yale School of Medicine)

  • Sangbum Park

    (Yale School of Medicine)

  • Catherine Matte-Martone

    (Yale School of Medicine)

  • David G. Gonzalez

    (Yale School of Medicine)

  • Julie Rytlewski

    (Fred Hutchinson Cancer Research Center)

  • Slobodan Beronja

    (Fred Hutchinson Cancer Research Center)

  • Valentina Greco

    (Yale School of Medicine
    Yale Stem Cell Center, Yale School of Medicine
    Yale Cancer Center, Yale School of Medicine
    Yale School of Medicine)

Abstract

Intravital imaging reveals unanticipated plasticity of adult skin epithelium in mice when faced with mutational or non-mutational insults, and elucidates the dynamic cellular behaviours used for its return to a homeostatic state.

Suggested Citation

  • Samara Brown & Cristiana M. Pineda & Tianchi Xin & Jonathan Boucher & Kathleen C. Suozzi & Sangbum Park & Catherine Matte-Martone & David G. Gonzalez & Julie Rytlewski & Slobodan Beronja & Valentina G, 2017. "Correction of aberrant growth preserves tissue homeostasis," Nature, Nature, vol. 548(7667), pages 334-337, August.
    • Handle: RePEc:nat:nature:v:548:y:2017:i:7667:d:10.1038_nature23304
    DOI: 10.1038/nature23304
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    Cited by:

    1. Kazuki Nakai & Hancheng Lin & Shotaro Yamano & Shinya Tanaka & Sho Kitamoto & Hitoshi Saitoh & Kenta Sakuma & Junpei Kurauchi & Eilma Akter & Masamitsu Konno & Kojiro Ishibashi & Ryo Kamata & Akihiro , 2023. "Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

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