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Rewiring the taste system

Author

Listed:
  • Hojoon Lee

    (Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University
    Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University)

  • Lindsey J. Macpherson

    (Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University
    Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University)

  • Camilo A. Parada

    (Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University
    Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University)

  • Charles S. Zuker

    (Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University
    Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University)

  • Nicholas J. P. Ryba

    (National Institute of Dental and Craniofacial Research, National Institutes of Health)

Abstract

Taste-receptor cells use distinct semaphorins to guide wiring of the peripheral taste system; targeted ectopic expression of SEMA3A or SEMA7A leads to bitter neurons responding to sweet tastes or sweet neurons responding to bitter tastes.

Suggested Citation

  • Hojoon Lee & Lindsey J. Macpherson & Camilo A. Parada & Charles S. Zuker & Nicholas J. P. Ryba, 2017. "Rewiring the taste system," Nature, Nature, vol. 548(7667), pages 330-333, August.
    • Handle: RePEc:nat:nature:v:548:y:2017:i:7667:d:10.1038_nature23299
    DOI: 10.1038/nature23299
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