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Allelic reprogramming of 3D chromatin architecture during early mammalian development

Author

Listed:
  • Zhenhai Du

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University)

  • Hui Zheng

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University)

  • Bo Huang

    (PKU-THU Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University)

  • Rui Ma

    (Institute for Interdisciplinary Information Sciences, Tsinghua University)

  • Jingyi Wu

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University
    Joint Graduate Program of Peking-Tsinghua-NIBS, School of Life Sciences, Tsinghua University)

  • Xianglin Zhang

    (MOE Key Laboratory of Bioinformatics
    TNLIST)

  • Jing He

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University)

  • Yunlong Xiang

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University)

  • Qiujun Wang

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University)

  • Yuanyuan Li

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University)

  • Jing Ma

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University)

  • Xu Zhang

    (MOE Key Laboratory of Bioinformatics
    TNLIST)

  • Ke Zhang

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University)

  • Yang Wang

    (MOE Key Laboratory of Bioinformatics
    TNLIST)

  • Michael Q. Zhang

    (MOE Key Laboratory of Bioinformatics
    TNLIST
    Center for Systems Biology, The University of Texas, Dallas 800 West Campbell Road, RL11 Richardson)

  • Juntao Gao

    (MOE Key Laboratory of Bioinformatics
    TNLIST)

  • Jesse R. Dixon

    (The Salk Institute for Biological Studies)

  • Xiaowo Wang

    (MOE Key Laboratory of Bioinformatics
    TNLIST)

  • Jianyang Zeng

    (Institute for Interdisciplinary Information Sciences, Tsinghua University)

  • Wei Xie

    (Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University
    Joint Graduate Program of Peking-Tsinghua-NIBS, School of Life Sciences, Tsinghua University)

Abstract

A low-input Hi-C method is used to show that chromatin organization is markedly relaxed in pre-implantation mouse embryos after fertilization and that the subsequent maturation of 3D chromatin architecture is surprisingly slow.

Suggested Citation

  • Zhenhai Du & Hui Zheng & Bo Huang & Rui Ma & Jingyi Wu & Xianglin Zhang & Jing He & Yunlong Xiang & Qiujun Wang & Yuanyuan Li & Jing Ma & Xu Zhang & Ke Zhang & Yang Wang & Michael Q. Zhang & Juntao Ga, 2017. "Allelic reprogramming of 3D chromatin architecture during early mammalian development," Nature, Nature, vol. 547(7662), pages 232-235, July.
    • Handle: RePEc:nat:nature:v:547:y:2017:i:7662:d:10.1038_nature23263
    DOI: 10.1038/nature23263
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    Citations

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    Cited by:

    1. Markus Götz & Olivier Messina & Sergio Espinola & Jean-Bernard Fiche & Marcelo Nollmann, 2022. "Multiple parameters shape the 3D chromatin structure of single nuclei at the doc locus in Drosophila," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    2. Jason Alexander Halliwell & Javier Martin-Gonzalez & Adnan Hashim & John Arne Dahl & Eva R. Hoffmann & Mads Lerdrup, 2024. "Sex-specific DNA-replication in the early mammalian embryo," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    3. Laureano Tomás-Daza & Llorenç Rovirosa & Paula López-Martí & Andrea Nieto-Aliseda & François Serra & Ainoa Planas-Riverola & Oscar Molina & Rebecca McDonald & Cedric Ghevaert & Esther Cuatrecasas & Do, 2023. "Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    4. Shuangyi Xu & Ning Wang & Michael V. Zuccaro & Jeannine Gerhardt & Rajan Iyyappan & Giovanna Nascimento Scatolin & Zongliang Jiang & Timour Baslan & Amnon Koren & Dieter Egli, 2024. "DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    5. Phoebe Lut Fei Tam & Ming Fung Cheung & Lu Yan Chan & Danny Leung, 2024. "Cell-type differential targeting of SETDB1 prevents aberrant CTCF binding, chromatin looping, and cis-regulatory interactions," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    6. Haoxi Chai & Harianto Tjong & Peng Li & Wei Liao & Ping Wang & Chee Hong Wong & Chew Yee Ngan & Warren J. Leonard & Chia-Lin Wei & Yijun Ruan, 2023. "ChIATAC is an efficient strategy for multi-omics mapping of 3D epigenomes from low-cell inputs," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
    7. Jia-Yong Zhong & Longjian Niu & Zhuo-Bin Lin & Xin Bai & Ying Chen & Feng Luo & Chunhui Hou & Chuan-Le Xiao, 2023. "High-throughput Pore-C reveals the single-allele topology and cell type-specificity of 3D genome folding," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
    8. Hua Yu & Zhen Sun & Tianyu Tan & Hongru Pan & Jing Zhao & Ling Zhang & Jiayu Chen & Anhua Lei & Yuqing Zhu & Lang Chen & Yuyan Xu & Yaxin Liu & Ming Chen & Jinghao Sheng & Zhengping Xu & Pengxu Qian &, 2021. "rRNA biogenesis regulates mouse 2C-like state by 3D structure reorganization of peri-nucleolar heterochromatin," Nature Communications, Nature, vol. 12(1), pages 1-21, December.

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