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RNase III nucleases from diverse kingdoms serve as antiviral effectors

Author

Listed:
  • Lauren C. Aguado

    (Icahn School of Medicine at Mount Sinai)

  • Sonja Schmid

    (Icahn School of Medicine at Mount Sinai)

  • Jared May

    (University of Maryland College Park)

  • Leah R. Sabin

    (University of Pennsylvania)

  • Maryline Panis

    (Icahn School of Medicine at Mount Sinai)

  • Daniel Blanco-Melo

    (Icahn School of Medicine at Mount Sinai)

  • Jaehee V. Shim

    (Icahn School of Medicine at Mount Sinai)

  • David Sachs

    (Icahn School of Medicine at Mount Sinai)

  • Sara Cherry

    (University of Pennsylvania)

  • Anne E. Simon

    (University of Maryland College Park)

  • Jean-Pierre Levraud

    (Macrophages et Développement de l’Immunité, Institut Pasteur, CNRS UMR3738)

  • Benjamin R. tenOever

    (Icahn School of Medicine at Mount Sinai)

Abstract

RNase III from all three domains of life elicits RNA-targeting antiviral activity that is independent of, and possibly predates, other known eukaryotic antiviral systems.

Suggested Citation

  • Lauren C. Aguado & Sonja Schmid & Jared May & Leah R. Sabin & Maryline Panis & Daniel Blanco-Melo & Jaehee V. Shim & David Sachs & Sara Cherry & Anne E. Simon & Jean-Pierre Levraud & Benjamin R. tenOe, 2017. "RNase III nucleases from diverse kingdoms serve as antiviral effectors," Nature, Nature, vol. 547(7661), pages 114-117, July.
    • Handle: RePEc:nat:nature:v:547:y:2017:i:7661:d:10.1038_nature22990
    DOI: 10.1038/nature22990
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