IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v546y2017i7659d10.1038_nature22796.html
   My bibliography  Save this article

Multilineage communication regulates human liver bud development from pluripotency

Author

Listed:
  • J. Gray Camp

    (Max Planck Institute for Evolutionary Anthropology)

  • Keisuke Sekine

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Tobias Gerber

    (Max Planck Institute for Evolutionary Anthropology)

  • Henry Loeffler-Wirth

    (Interdisciplinary Centre for Bioinformatics, Leipzig University)

  • Hans Binder

    (Interdisciplinary Centre for Bioinformatics, Leipzig University)

  • Malgorzata Gac

    (Max Planck Institute for Evolutionary Anthropology)

  • Sabina Kanton

    (Max Planck Institute for Evolutionary Anthropology)

  • Jorge Kageyama

    (Max Planck Institute for Evolutionary Anthropology)

  • Georg Damm

    (University Hospital of Leipzig
    Saxonian Incubator for Clinical Translation (SIKT), University of Leipzig)

  • Daniel Seehofer

    (University Hospital of Leipzig
    Saxonian Incubator for Clinical Translation (SIKT), University of Leipzig)

  • Lenka Belicova

    (Max Planck Institute of Molecular Cell Biology and Genetics)

  • Marc Bickle

    (Max Planck Institute of Molecular Cell Biology and Genetics)

  • Rico Barsacchi

    (Max Planck Institute of Molecular Cell Biology and Genetics)

  • Ryo Okuda

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Emi Yoshizawa

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Masaki Kimura

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Hiroaki Ayabe

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Hideki Taniguchi

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Takanori Takebe

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku
    Cincinnati Children’s Hospital Medical Center, University of Cincinnati)

  • Barbara Treutlein

    (Max Planck Institute for Evolutionary Anthropology
    Max Planck Institute of Molecular Cell Biology and Genetics)

Abstract

Single-cell RNA sequencing analysis of two- and three-dimensional hepatic differentiation reveals that both systems recapitulate certain transcriptomic features of human hepatogenesis.

Suggested Citation

  • J. Gray Camp & Keisuke Sekine & Tobias Gerber & Henry Loeffler-Wirth & Hans Binder & Malgorzata Gac & Sabina Kanton & Jorge Kageyama & Georg Damm & Daniel Seehofer & Lenka Belicova & Marc Bickle & Ric, 2017. "Multilineage communication regulates human liver bud development from pluripotency," Nature, Nature, vol. 546(7659), pages 533-538, June.
    • Handle: RePEc:nat:nature:v:546:y:2017:i:7659:d:10.1038_nature22796
    DOI: 10.1038/nature22796
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature22796
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature22796?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Maisumu Gulimiheranmu & Shuang Li & Junmei Zhou, 2021. "In Vitro Recapitulation of Neuropsychiatric Disorders with Pluripotent Stem Cells-Derived Brain Organoids," IJERPH, MDPI, vol. 18(23), pages 1-14, November.
    2. Peizhuo Wang & Xiao Wen & Han Li & Peng Lang & Shuya Li & Yipin Lei & Hantao Shu & Lin Gao & Dan Zhao & Jianyang Zeng, 2023. "Deciphering driver regulators of cell fate decisions from single-cell transcriptomics data with CEFCON," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    3. Chieh Lin & Jun Ding & Ziv Bar-Joseph, 2020. "Inferring TF activation order in time series scRNA-Seq studies," PLOS Computational Biology, Public Library of Science, vol. 16(2), pages 1-19, February.
    4. Jing Qi & Yang Zhou & Zicen Zhao & Shuilin Jin, 2021. "SDImpute: A statistical block imputation method based on cell-level and gene-level information for dropouts in single-cell RNA-seq data," PLOS Computational Biology, Public Library of Science, vol. 17(6), pages 1-20, June.
    5. Erica Carolina & Yoshiki Kuse & Ayumu Okumura & Kenji Aoshima & Tomomi Tadokoro & Shinya Matsumoto & Eriko Kanai & Takashi Okumura & Toshiharu Kasai & Souichiro Yamabe & Yuji Nishikawa & Kiyoshi Yamag, 2024. "Generation of human iPSC-derived 3D bile duct within liver organoid by incorporating human iPSC-derived blood vessel," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    6. Wenwei Sun & Meimei Wang & Jun Zhao & Shuang Zhao & Wenchao Zhu & Xiaoting Wu & Feifei Li & Wei Liu & Zhuo Wang & Meng Gao & Yiyue Zhang & Jin Xu & Meijia Zhang & Qiang Wang & Zilong Wen & Juan Shen &, 2023. "Sulindac selectively induces autophagic apoptosis of GABAergic neurons and alters motor behaviour in zebrafish," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:546:y:2017:i:7659:d:10.1038_nature22796. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.