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Multilineage communication regulates human liver bud development from pluripotency

Author

Listed:
  • J. Gray Camp

    (Max Planck Institute for Evolutionary Anthropology)

  • Keisuke Sekine

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Tobias Gerber

    (Max Planck Institute for Evolutionary Anthropology)

  • Henry Loeffler-Wirth

    (Interdisciplinary Centre for Bioinformatics, Leipzig University)

  • Hans Binder

    (Interdisciplinary Centre for Bioinformatics, Leipzig University)

  • Malgorzata Gac

    (Max Planck Institute for Evolutionary Anthropology)

  • Sabina Kanton

    (Max Planck Institute for Evolutionary Anthropology)

  • Jorge Kageyama

    (Max Planck Institute for Evolutionary Anthropology)

  • Georg Damm

    (University Hospital of Leipzig
    Saxonian Incubator for Clinical Translation (SIKT), University of Leipzig)

  • Daniel Seehofer

    (University Hospital of Leipzig
    Saxonian Incubator for Clinical Translation (SIKT), University of Leipzig)

  • Lenka Belicova

    (Max Planck Institute of Molecular Cell Biology and Genetics)

  • Marc Bickle

    (Max Planck Institute of Molecular Cell Biology and Genetics)

  • Rico Barsacchi

    (Max Planck Institute of Molecular Cell Biology and Genetics)

  • Ryo Okuda

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Emi Yoshizawa

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Masaki Kimura

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Hiroaki Ayabe

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Hideki Taniguchi

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku)

  • Takanori Takebe

    (Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku
    Cincinnati Children’s Hospital Medical Center, University of Cincinnati)

  • Barbara Treutlein

    (Max Planck Institute for Evolutionary Anthropology
    Max Planck Institute of Molecular Cell Biology and Genetics)

Abstract

Single-cell RNA sequencing analysis of two- and three-dimensional hepatic differentiation reveals that both systems recapitulate certain transcriptomic features of human hepatogenesis.

Suggested Citation

  • J. Gray Camp & Keisuke Sekine & Tobias Gerber & Henry Loeffler-Wirth & Hans Binder & Malgorzata Gac & Sabina Kanton & Jorge Kageyama & Georg Damm & Daniel Seehofer & Lenka Belicova & Marc Bickle & Ric, 2017. "Multilineage communication regulates human liver bud development from pluripotency," Nature, Nature, vol. 546(7659), pages 533-538, June.
    • Handle: RePEc:nat:nature:v:546:y:2017:i:7659:d:10.1038_nature22796
    DOI: 10.1038/nature22796
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    Citations

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    Cited by:

    1. Maisumu Gulimiheranmu & Shuang Li & Junmei Zhou, 2021. "In Vitro Recapitulation of Neuropsychiatric Disorders with Pluripotent Stem Cells-Derived Brain Organoids," IJERPH, MDPI, vol. 18(23), pages 1-14, November.
    2. Peizhuo Wang & Xiao Wen & Han Li & Peng Lang & Shuya Li & Yipin Lei & Hantao Shu & Lin Gao & Dan Zhao & Jianyang Zeng, 2023. "Deciphering driver regulators of cell fate decisions from single-cell transcriptomics data with CEFCON," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    3. Chieh Lin & Jun Ding & Ziv Bar-Joseph, 2020. "Inferring TF activation order in time series scRNA-Seq studies," PLOS Computational Biology, Public Library of Science, vol. 16(2), pages 1-19, February.
    4. Jing Qi & Yang Zhou & Zicen Zhao & Shuilin Jin, 2021. "SDImpute: A statistical block imputation method based on cell-level and gene-level information for dropouts in single-cell RNA-seq data," PLOS Computational Biology, Public Library of Science, vol. 17(6), pages 1-20, June.
    5. Wenwei Sun & Meimei Wang & Jun Zhao & Shuang Zhao & Wenchao Zhu & Xiaoting Wu & Feifei Li & Wei Liu & Zhuo Wang & Meng Gao & Yiyue Zhang & Jin Xu & Meijia Zhang & Qiang Wang & Zilong Wen & Juan Shen &, 2023. "Sulindac selectively induces autophagic apoptosis of GABAergic neurons and alters motor behaviour in zebrafish," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

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