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KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks

Author

Listed:
  • Michaël Imbeault

    (School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL))

  • Pierre-Yves Helleboid

    (School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL))

  • Didier Trono

    (School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL))

Abstract

Genomic analyses of KRAB-containing zinc-finger proteins and the transposable elements to which they bind show that a co-evolutionary arms race was not the only driver of their evolution.

Suggested Citation

  • Michaël Imbeault & Pierre-Yves Helleboid & Didier Trono, 2017. "KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks," Nature, Nature, vol. 543(7646), pages 550-554, March.
    • Handle: RePEc:nat:nature:v:543:y:2017:i:7646:d:10.1038_nature21683
    DOI: 10.1038/nature21683
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    Cited by:

    1. Daniel F. Kaemena & Masahito Yoshihara & Meryam Beniazza & James Ashmore & Suling Zhao & Mårten Bertenstam & Victor Olariu & Shintaro Katayama & Keisuke Okita & Simon R. Tomlinson & Kosuke Yusa & Keis, 2023. "B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factors," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    2. Laia Simó-Riudalbas & Sandra Offner & Evarist Planet & Julien Duc & Laurence Abrami & Sagane Dind & Alexandre Coudray & Mairene Coto-Llerena & Caner Ercan & Salvatore Piscuoglio & Claus Lindbjerg Ande, 2022. "Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
    3. Nikolaos M. R. Lykoskoufis & Evarist Planet & Halit Ongen & Didier Trono & Emmanouil T. Dermitzakis, 2024. "Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    4. Konsta Karttunen & Divyesh Patel & Jihan Xia & Liangru Fei & Kimmo Palin & Lauri Aaltonen & Biswajyoti Sahu, 2023. "Transposable elements as tissue-specific enhancers in cancers of endodermal lineage," Nature Communications, Nature, vol. 14(1), pages 1-19, December.

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