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Remote site-selective C–H activation directed by a catalytic bifunctional template

Author

Listed:
  • Zhipeng Zhang

    (The Scripps Research Institute)

  • Keita Tanaka

    (The Scripps Research Institute)

  • Jin-Quan Yu

    (The Scripps Research Institute)

Abstract

A method is described for selectively activating remote C–H bonds in heterocycles by using a catalytic template that binds by reversible coordination instead of a covalent linkage, removing the need for specific functional groups on which to attach the template.

Suggested Citation

  • Zhipeng Zhang & Keita Tanaka & Jin-Quan Yu, 2017. "Remote site-selective C–H activation directed by a catalytic bifunctional template," Nature, Nature, vol. 543(7646), pages 538-542, March.
  • Handle: RePEc:nat:nature:v:543:y:2017:i:7646:d:10.1038_nature21418
    DOI: 10.1038/nature21418
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    Cited by:

    1. Saikat Guria & Mirja Md Mahamudul Hassan & Jiawei Ma & Sayan Dey & Yong Liang & Buddhadeb Chattopadhyay, 2023. "A tautomerized ligand enabled meta selective C–H borylation of phenol," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    2. Longlong Xi & Minyan Wang & Yong Liang & Yue Zhao & Zhuangzhi Shi, 2023. "Tunably strained metallacycles enable modular differentiation of aza-arene C–H bonds," Nature Communications, Nature, vol. 14(1), pages 1-10, December.

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