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Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer

Author

Listed:
  • Di Zhao

    (The University of Texas MD Anderson Cancer Center)

  • Xin Lu

    (The University of Texas MD Anderson Cancer Center)

  • Guocan Wang

    (The University of Texas MD Anderson Cancer Center)

  • Zhengdao Lan

    (The University of Texas MD Anderson Cancer Center)

  • Wenting Liao

    (The University of Texas MD Anderson Cancer Center)

  • Jun Li

    (The University of Texas MD Anderson Cancer Center)

  • Xin Liang

    (The University of Texas MD Anderson Cancer Center)

  • Jasper Robin Chen

    (The University of Texas MD Anderson Cancer Center)

  • Sagar Shah

    (The University of Texas MD Anderson Cancer Center)

  • Xiaoying Shang

    (The University of Texas MD Anderson Cancer Center)

  • Ming Tang

    (The University of Texas MD Anderson Cancer Center)

  • Pingna Deng

    (The University of Texas MD Anderson Cancer Center)

  • Prasenjit Dey

    (The University of Texas MD Anderson Cancer Center)

  • Deepavali Chakravarti

    (The University of Texas MD Anderson Cancer Center)

  • Peiwen Chen

    (The University of Texas MD Anderson Cancer Center)

  • Denise J. Spring

    (The University of Texas MD Anderson Cancer Center)

  • Nora M. Navone

    (The University of Texas MD Anderson Cancer Center)

  • Patricia Troncoso

    (The University of Texas MD Anderson Cancer Center)

  • Jianhua Zhang

    (The University of Texas MD Anderson Cancer Center)

  • Y. Alan Wang

    (The University of Texas MD Anderson Cancer Center)

  • Ronald A. DePinho

    (The University of Texas MD Anderson Cancer Center)

Abstract

The gene CHD1 is synthetic essential in PTEN-deficient prostate and breast cancers.

Suggested Citation

  • Di Zhao & Xin Lu & Guocan Wang & Zhengdao Lan & Wenting Liao & Jun Li & Xin Liang & Jasper Robin Chen & Sagar Shah & Xiaoying Shang & Ming Tang & Pingna Deng & Prasenjit Dey & Deepavali Chakravarti & , 2017. "Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer," Nature, Nature, vol. 542(7642), pages 484-488, February.
    • Handle: RePEc:nat:nature:v:542:y:2017:i:7642:d:10.1038_nature21357
    DOI: 10.1038/nature21357
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    Cited by:

    1. Jian Ma & Lei Li & Bohan Ma & Tianjie Liu & Zixi Wang & Qi Ye & Yunhua Peng & Bin Wang & Yule Chen & Shan Xu & Ke Wang & Fabin Dang & Xinyang Wang & Zixuan Zeng & Yanlin Jian & Zhihua Ren & Yizeng Fan, 2024. "MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    2. Ilya G. Serebriiskii & Valery Pavlov & Rossella Tricarico & Grigorii Andrianov & Emmanuelle Nicolas & Mitchell I. Parker & Justin Newberg & Garrett Frampton & Joshua E. Meyer & Erica A. Golemis, 2022. "Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers," Nature Communications, Nature, vol. 13(1), pages 1-17, December.

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