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Feedback control of AHR signalling regulates intestinal immunity

Author

Listed:
  • Chris Schiering

    (The Francis Crick Institute)

  • Emma Wincent

    (Swedish Toxicology Sciences Research Center)

  • Amina Metidji

    (The Francis Crick Institute)

  • Andrea Iseppon

    (The Francis Crick Institute)

  • Ying Li

    (The Francis Crick Institute)

  • Alexandre J. Potocnik

    (Institute of Immunology and Infection Research, The University of Edinburgh)

  • Sara Omenetti

    (The Francis Crick Institute)

  • Colin J. Henderson

    (Dundee University School of Medicine)

  • C. Roland Wolf

    (Dundee University School of Medicine)

  • Daniel W. Nebert

    (University of Cincinnati)

  • Brigitta Stockinger

    (The Francis Crick Institute)

Abstract

Cytochrome P4501 enzymes have a role in the regulation of aryl hydrocarbon receptor ligand levels in the gut, affecting innate lymphoid and TH17 cell responses.

Suggested Citation

  • Chris Schiering & Emma Wincent & Amina Metidji & Andrea Iseppon & Ying Li & Alexandre J. Potocnik & Sara Omenetti & Colin J. Henderson & C. Roland Wolf & Daniel W. Nebert & Brigitta Stockinger, 2017. "Feedback control of AHR signalling regulates intestinal immunity," Nature, Nature, vol. 542(7640), pages 242-245, February.
    • Handle: RePEc:nat:nature:v:542:y:2017:i:7640:d:10.1038_nature21080
    DOI: 10.1038/nature21080
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    Cited by:

    1. Kathleen Shah & Muralidhara Rao Maradana & M. Joaquina Delàs & Amina Metidji & Frederike Graelmann & Miriam Llorian & Probir Chakravarty & Ying Li & Mauro Tolaini & Michael Shapiro & Gavin Kelly & Chr, 2022. "Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    2. Xiuchuan (Lucas) Hu & Wenfeng Xiao & Yuxian Lei & Adam Green & Xinyi Lee & Muralidhara Rao Maradana & Yajing Gao & Xueru Xie & Rui Wang & George Chennell & M. Albert Basson & Pete Kille & Wolfgang Mar, 2023. "Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier," Nature Communications, Nature, vol. 14(1), pages 1-15, December.

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