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Fetal liver endothelium regulates the seeding of tissue-resident macrophages

Author

Listed:
  • Pia Rantakari

    (MediCity Research Laboratory, University of Turku)

  • Norma Jäppinen

    (MediCity Research Laboratory, University of Turku)

  • Emmi Lokka

    (MediCity Research Laboratory, University of Turku)

  • Elias Mokkala

    (MediCity Research Laboratory, University of Turku)

  • Heidi Gerke

    (MediCity Research Laboratory, University of Turku)

  • Emilia Peuhu

    (Turku Centre for Biotechnology, University of Turku)

  • Johanna Ivaska

    (Turku Centre for Biotechnology, University of Turku
    University of Turku)

  • Kati Elima

    (MediCity Research Laboratory, University of Turku
    University of Turku)

  • Kaisa Auvinen

    (MediCity Research Laboratory, University of Turku)

  • Marko Salmi

    (MediCity Research Laboratory, University of Turku
    University of Turku)

Abstract

PLVAP selectively controls the seeding of fetal liver monocyte-derived tissue-resident macrophages, seemingly by interacting with chemotactic and adhesive molecules at the diaphragms of liver sinusoidal endothelium.

Suggested Citation

  • Pia Rantakari & Norma Jäppinen & Emmi Lokka & Elias Mokkala & Heidi Gerke & Emilia Peuhu & Johanna Ivaska & Kati Elima & Kaisa Auvinen & Marko Salmi, 2016. "Fetal liver endothelium regulates the seeding of tissue-resident macrophages," Nature, Nature, vol. 538(7625), pages 392-396, October.
    • Handle: RePEc:nat:nature:v:538:y:2016:i:7625:d:10.1038_nature19814
    DOI: 10.1038/nature19814
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