IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v535y2016i7613d10.1038_nature18647.html
   My bibliography  Save this article

Dynamics of ribosome scanning and recycling revealed by translation complex profiling

Author

Listed:
  • Stuart K. Archer

    (EMBL–Australia Collaborating Group, The John Curtin School of Medical Research, The Australian National University
    Monash Bioinformatics Platform, Monash University)

  • Nikolay E. Shirokikh

    (EMBL–Australia Collaborating Group, The John Curtin School of Medical Research, The Australian National University
    Moscow Regional State Institute of Humanities and Social Studies)

  • Traude H. Beilharz

    (Development and Stem Cells Program, Monash University)

  • Thomas Preiss

    (EMBL–Australia Collaborating Group, The John Curtin School of Medical Research, The Australian National University
    Victor Chang Cardiac Research Institute)

Abstract

A translation complex sequencing approach has been developed enabling intermediates of all mRNA-associated processes of translation to be isolated and localized across the transcriptome; the results support longstanding models of initiation and termination and offer new mechanistic insights.

Suggested Citation

  • Stuart K. Archer & Nikolay E. Shirokikh & Traude H. Beilharz & Thomas Preiss, 2016. "Dynamics of ribosome scanning and recycling revealed by translation complex profiling," Nature, Nature, vol. 535(7613), pages 570-574, July.
    • Handle: RePEc:nat:nature:v:535:y:2016:i:7613:d:10.1038_nature18647
    DOI: 10.1038/nature18647
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature18647
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature18647?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Yifei Gu & Yuanhui Mao & Longfei Jia & Leiming Dong & Shu-Bing Qian, 2021. "Bi-directional ribosome scanning controls the stringency of start codon selection," Nature Communications, Nature, vol. 12(1), pages 1-12, December.
    2. Pietro Bongini & Niccolò Pancino & Veronica Lachi & Caterina Graziani & Giorgia Giacomini & Paolo Andreini & Monica Bianchini, 2024. "Point-Wise Ribosome Translation Speed Prediction with Recurrent Neural Networks," Mathematics, MDPI, vol. 12(3), pages 1-12, January.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:535:y:2016:i:7613:d:10.1038_nature18647. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.