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MARCKS-like protein is an initiating molecule in axolotl appendage regeneration

Author

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  • Takuji Sugiura

    (DFG Research Center for Regenerative Therapies (CRTD), Technische Universität Dresden
    Max Planck Institute for Molecular Cell Biology and Genetics
    †Present address: DFG Research Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany.)

  • Heng Wang

    (Karolinska Institute, Centre of Developmental Biology for Regenerative Medicine)

  • Rico Barsacchi

    (Max Planck Institute for Molecular Cell Biology and Genetics)

  • Andras Simon

    (Karolinska Institute, Centre of Developmental Biology for Regenerative Medicine)

  • Elly M. Tanaka

    (DFG Research Center for Regenerative Therapies (CRTD), Technische Universität Dresden
    Max Planck Institute for Molecular Cell Biology and Genetics
    †Present address: DFG Research Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany.)

Abstract

The salamander, or axolotl, is well known to be able to regenerate missing body parts, but the signals that drive the initial proliferative response were unclear; now, a secreted protein has been identified that induces the initial cell cycle response after injury.

Suggested Citation

  • Takuji Sugiura & Heng Wang & Rico Barsacchi & Andras Simon & Elly M. Tanaka, 2016. "MARCKS-like protein is an initiating molecule in axolotl appendage regeneration," Nature, Nature, vol. 531(7593), pages 237-240, March.
    • Handle: RePEc:nat:nature:v:531:y:2016:i:7593:d:10.1038_nature16974
    DOI: 10.1038/nature16974
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