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The sexual identity of adult intestinal stem cells controls organ size and plasticity

Author

Listed:
  • Bruno Hudry

    (MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus)

  • Sanjay Khadayate

    (MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus)

  • Irene Miguel-Aliaga

    (MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus)

Abstract

Reversible, cell-intrinsic mechanisms that depend on a new sex differentiation pathway act in adult somatic cells of the Drosophila intestine to govern sex-specific differences in organ size, plasticity during reproduction, and response to tumorigenic insults.

Suggested Citation

  • Bruno Hudry & Sanjay Khadayate & Irene Miguel-Aliaga, 2016. "The sexual identity of adult intestinal stem cells controls organ size and plasticity," Nature, Nature, vol. 530(7590), pages 344-348, February.
    • Handle: RePEc:nat:nature:v:530:y:2016:i:7590:d:10.1038_nature16953
    DOI: 10.1038/nature16953
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    Cited by:

    1. Omid Omrani & Anna Krepelova & Seyed Mohammad Mahdi Rasa & Dovydas Sirvinskas & Jing Lu & Francesco Annunziata & George Garside & Seerat Bajwa & Susanne Reinhardt & Lisa Adam & Sandra Käppel & Nadia D, 2023. "IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
    2. Tom W. Andrew & Lauren S. Koepke & Yuting Wang & Michael Lopez & Holly Steininger & Danielle Struck & Tatiana Boyko & Thomas H. Ambrosi & Xinming Tong & Yuxi Sun & Gunsagar S. Gulati & Matthew P. Murp, 2022. "Sexually dimorphic estrogen sensing in skeletal stem cells controls skeletal regeneration," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    3. Chloé Hérault & Thomas Pihl & Bruno Hudry, 2024. "Cellular sex throughout the organism underlies somatic sexual differentiation," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    4. Oksana Netschitailo & Yidong Wang & Anna Wagner & Vivien Sommer & Eveline C. Verhulst & Martin Beye, 2023. "The function and evolution of a genetic switch controlling sexually dimorphic eye differentiation in honeybees," Nature Communications, Nature, vol. 14(1), pages 1-14, December.

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