IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v530y2016i7590d10.1038_nature16937.html
   My bibliography  Save this article

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

Author

Listed:
  • Henner F. Farin

    (Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht
    German Cancer Consortium (DKTK)
    Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy
    German Cancer Research Center (DKFZ))

  • Ingrid Jordens

    (Center for Molecular Medicine, University Medical Center Utrecht)

  • Mohammed H. Mosa

    (German Cancer Consortium (DKTK)
    Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy
    German Cancer Research Center (DKFZ))

  • Onur Basak

    (Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht)

  • Jeroen Korving

    (Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht)

  • Daniele V. F. Tauriello

    (Center for Molecular Medicine, University Medical Center Utrecht)

  • Karin de Punder

    (The Maastricht Multimodal Molecular Imaging institute, Maastricht University)

  • Stephane Angers

    (Leslie Dan Faculty of Pharmacy, University of Toronto)

  • Peter J. Peters

    (The Maastricht Multimodal Molecular Imaging institute, Maastricht University)

  • Madelon M. Maurice

    (Center for Molecular Medicine, University Medical Center Utrecht)

  • Hans Clevers

    (Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht)

Abstract

Generation of an epitope-tagged, functional Wnt3 knock-in allele, the signal produced by Paneth cells to regulate intestinal stem cells.

Suggested Citation

  • Henner F. Farin & Ingrid Jordens & Mohammed H. Mosa & Onur Basak & Jeroen Korving & Daniele V. F. Tauriello & Karin de Punder & Stephane Angers & Peter J. Peters & Madelon M. Maurice & Hans Clevers, 2016. "Visualization of a short-range Wnt gradient in the intestinal stem-cell niche," Nature, Nature, vol. 530(7590), pages 340-343, February.
    • Handle: RePEc:nat:nature:v:530:y:2016:i:7590:d:10.1038_nature16937
    DOI: 10.1038/nature16937
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature16937
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature16937?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:530:y:2016:i:7590:d:10.1038_nature16937. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.