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Polarized endosome dynamics by spindle asymmetry during asymmetric cell division

Author

Listed:
  • Emmanuel Derivery

    (Faculty of Sciences, University of Geneva)

  • Carole Seum

    (Faculty of Sciences, University of Geneva)

  • Alicia Daeden

    (Faculty of Sciences, University of Geneva)

  • Sylvain Loubéry

    (Faculty of Sciences, University of Geneva)

  • Laurent Holtzer

    (Faculty of Sciences, University of Geneva)

  • Frank Jülicher

    (Max Planck Institute for the Physics of Complex Systems)

  • Marcos Gonzalez-Gaitan

    (Faculty of Sciences, University of Geneva)

Abstract

Central spindle asymmetry, generated by the kinesin Klp10A and its antagonist Patronin, polarizes endosome motility and provides a mechanism for the asymmetric segregation of signalling endosomes observed in a variety of asymmetrically dividing cell types.

Suggested Citation

  • Emmanuel Derivery & Carole Seum & Alicia Daeden & Sylvain Loubéry & Laurent Holtzer & Frank Jülicher & Marcos Gonzalez-Gaitan, 2015. "Polarized endosome dynamics by spindle asymmetry during asymmetric cell division," Nature, Nature, vol. 528(7581), pages 280-285, December.
    • Handle: RePEc:nat:nature:v:528:y:2015:i:7581:d:10.1038_nature16443
    DOI: 10.1038/nature16443
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