IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v528y2015i7581d10.1038_nature15742.html
   My bibliography  Save this article

Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells

Author

Listed:
  • Long V. Nguyen

    (Terry Fox Laboratory, BC Cancer Agency)

  • Davide Pellacani

    (Terry Fox Laboratory, BC Cancer Agency
    University of British Columbia)

  • Sylvain Lefort

    (Terry Fox Laboratory, BC Cancer Agency)

  • Nagarajan Kannan

    (Terry Fox Laboratory, BC Cancer Agency
    University of British Columbia)

  • Tomo Osako

    (University of British Columbia
    BC Cancer Agency)

  • Maisam Makarem

    (Terry Fox Laboratory, BC Cancer Agency)

  • Claire L. Cox

    (Terry Fox Laboratory, BC Cancer Agency)

  • William Kennedy

    (Terry Fox Laboratory, BC Cancer Agency)

  • Philip Beer

    (Terry Fox Laboratory, BC Cancer Agency)

  • Annaick Carles

    (Centre for High-Throughput Biology, University of British Columbia)

  • Michelle Moksa

    (Centre for High-Throughput Biology, University of British Columbia)

  • Misha Bilenky

    (Centre for High-Throughput Biology, University of British Columbia
    Canada’s Michael Smith Genome Sciences Centre, BC Cancer Agency)

  • Sneha Balani

    (Terry Fox Laboratory, BC Cancer Agency)

  • Sonja Babovic

    (Terry Fox Laboratory, BC Cancer Agency)

  • Ivan Sun

    (Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive
    Cancer Control Unit, BC Cancer Agency)

  • Miriam Rosin

    (Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive
    Cancer Control Unit, BC Cancer Agency)

  • Samuel Aparicio

    (University of British Columbia
    BC Cancer Agency)

  • Martin Hirst

    (Centre for High-Throughput Biology, University of British Columbia
    Canada’s Michael Smith Genome Sciences Centre, BC Cancer Agency)

  • Connie J. Eaves

    (Terry Fox Laboratory, BC Cancer Agency
    University of British Columbia)

Abstract

The first formal evidence of the shared and independent ability of basal cells and luminal pro-genitors isolated from normal human mammary tissue and transduced with a single oncogene to initiate tumorigeneses when introduced into mice.

Suggested Citation

  • Long V. Nguyen & Davide Pellacani & Sylvain Lefort & Nagarajan Kannan & Tomo Osako & Maisam Makarem & Claire L. Cox & William Kennedy & Philip Beer & Annaick Carles & Michelle Moksa & Misha Bilenky & , 2015. "Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells," Nature, Nature, vol. 528(7581), pages 267-271, December.
    • Handle: RePEc:nat:nature:v:528:y:2015:i:7581:d:10.1038_nature15742
    DOI: 10.1038/nature15742
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature15742
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature15742?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:528:y:2015:i:7581:d:10.1038_nature15742. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.