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Assassins of eyesight

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  • Andrew D. Huberman

    (Andrew D. Huberman and Rana N. El-Danaf are in the Neurobiology Section, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA.
    A.D.H. is also at the Salk Institute for Biological Studies, La Jolla.)

  • Rana N. El-Danaf

    (Andrew D. Huberman and Rana N. El-Danaf are in the Neurobiology Section, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA.)

Abstract

A molecular cascade involving the transcription factor SIX6 and its target gene p16INK4a causes the death of neurons that link the eye to the brain. This discovery deepens our understanding of a common form of blindness, glaucoma.

Suggested Citation

  • Andrew D. Huberman & Rana N. El-Danaf, 2015. "Assassins of eyesight," Nature, Nature, vol. 527(7579), pages 456-457, November.
    • Handle: RePEc:nat:nature:v:527:y:2015:i:7579:d:10.1038_527456a
    DOI: 10.1038/527456a
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