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Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic

Author

Listed:
  • Etienne Simon-Loriere

    (Institut Pasteur, Functional Genetics of Infectious Diseases Unit
    CNRS URA3012)

  • Ousmane Faye

    (Institut Pasteur de Dakar, Arbovirus and Viral Hemorrhagic Fever Unit)

  • Oumar Faye

    (Institut Pasteur de Dakar, Arbovirus and Viral Hemorrhagic Fever Unit)

  • Lamine Koivogui

    (Institut National de Santé Publique de Guinée)

  • Nfaly Magassouba

    (Projet de fièvres hémorragiques de Guinée, Université Gamal Abdel Nasser)

  • Sakoba Keita

    (Ministry of Health)

  • Jean-Michel Thiberge

    (Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence)

  • Laure Diancourt

    (Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence)

  • Christiane Bouchier

    (Institut Pasteur, Genomic platform)

  • Matthias Vandenbogaert

    (Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence)

  • Valérie Caro

    (Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence)

  • Gamou Fall

    (Institut Pasteur de Dakar, Arbovirus and Viral Hemorrhagic Fever Unit)

  • Jan P. Buchmann

    (Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Biological Sciences and Sydney Medical School, The University of Sydney)

  • Christan B. Matranga

    (Broad Institute)

  • Pardis C. Sabeti

    (Broad Institute
    FAS Center for Systems Biology, Harvard University)

  • Jean-Claude Manuguerra

    (Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence)

  • Edward C. Holmes

    (Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Biological Sciences and Sydney Medical School, The University of Sydney)

  • Amadou A. Sall

    (Institut Pasteur de Dakar, Arbovirus and Viral Hemorrhagic Fever Unit)

Abstract

An analysis of 85 Ebola virus sequences collected in Guinea from July to November 2014 provides insight into the evolution of the Ebola virus responsible for the epidemic in West Africa; the results show sustained transmission of three co-circulating lineages, each defined by multiple mutations.

Suggested Citation

  • Etienne Simon-Loriere & Ousmane Faye & Oumar Faye & Lamine Koivogui & Nfaly Magassouba & Sakoba Keita & Jean-Michel Thiberge & Laure Diancourt & Christiane Bouchier & Matthias Vandenbogaert & Valérie , 2015. "Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic," Nature, Nature, vol. 524(7563), pages 102-104, August.
    • Handle: RePEc:nat:nature:v:524:y:2015:i:7563:d:10.1038_nature14612
    DOI: 10.1038/nature14612
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