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A dendritic-cell brake on antitumour immunity

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  • Miriam Merad

    (Miriam Merad and Hélène Salmon are at the Tisch Cancer and Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.)

  • Hélène Salmon

    (Miriam Merad and Hélène Salmon are at the Tisch Cancer and Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.)

Abstract

Activation of a cellular stress response and the transcription factor XBP1 in dendritic cells has now been shown to limit the cells' ability to stimulate antitumour immune responses in a mouse model of ovarian cancer.

Suggested Citation

  • Miriam Merad & Hélène Salmon, 2015. "A dendritic-cell brake on antitumour immunity," Nature, Nature, vol. 523(7560), pages 294-295, July.
    • Handle: RePEc:nat:nature:v:523:y:2015:i:7560:d:10.1038_523294a
    DOI: 10.1038/523294a
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