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Spatiotemporal control of a novel synaptic organizer molecule

Author

Listed:
  • Kelly Howell

    (Howard Hughes Medical Institute, Columbia University Medical Center)

  • John G. White

    (MRC Laboratory of Molecular Biology)

  • Oliver Hobert

    (Howard Hughes Medical Institute, Columbia University Medical Center)

Abstract

Neuronal synapses need to be formed at the right time and the right place during nervous system development; here, three gene-regulatory factors (the UNC-30, LIN-14 and UNC-55 DNA-binding proteins) are shown to operate in an intersectional manner to control the expression of a novel synaptic organizer molecule, OIG-1.

Suggested Citation

  • Kelly Howell & John G. White & Oliver Hobert, 2015. "Spatiotemporal control of a novel synaptic organizer molecule," Nature, Nature, vol. 523(7558), pages 83-87, July.
    • Handle: RePEc:nat:nature:v:523:y:2015:i:7558:d:10.1038_nature14545
    DOI: 10.1038/nature14545
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    Cited by:

    1. Kellianne D. Alexander & Shankar Ramachandran & Kasturi Biswas & Christopher M. Lambert & Julia Russell & Devyn B. Oliver & William Armstrong & Monika Rettler & Samuel Liu & Maria Doitsidou & Claire B, 2023. "The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling," Nature Communications, Nature, vol. 14(1), pages 1-20, December.

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