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Structures of actin-like ParM filaments show architecture of plasmid-segregating spindles

Author

Listed:
  • Tanmay A. M. Bharat

    (MRC Laboratory of Molecular Biology)

  • Garib N. Murshudov

    (MRC Laboratory of Molecular Biology)

  • Carsten Sachse

    (Structural and Computational Biology Unit, European Molecular Biology Laboratory)

  • Jan Löwe

    (MRC Laboratory of Molecular Biology)

Abstract

Structures of actin-like ParM filaments at near-atomic resolution and their arrangements into doublets reveal how subunits and filaments come together to segregate low-copy-number plasmid R1 in Escherichia coli, producing the simplest known mitotic machinery.

Suggested Citation

  • Tanmay A. M. Bharat & Garib N. Murshudov & Carsten Sachse & Jan Löwe, 2015. "Structures of actin-like ParM filaments show architecture of plasmid-segregating spindles," Nature, Nature, vol. 523(7558), pages 106-110, July.
  • Handle: RePEc:nat:nature:v:523:y:2015:i:7558:d:10.1038_nature14356
    DOI: 10.1038/nature14356
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