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The micronucleus gets its big break

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  • Kristin A. Knouse

    (Kristin A. Knouse and Angelika Amon are at the Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.)

  • Angelika Amon

    (Kristin A. Knouse and Angelika Amon are at the Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.)

Abstract

Extensive chromosomal rearrangement – chromothripsis – is seen in several cancers. Imaging and sequencing of single cells shows that this phenomenon can occur inside cellular anomalies known as micronuclei. See Article p.179

Suggested Citation

  • Kristin A. Knouse & Angelika Amon, 2015. "The micronucleus gets its big break," Nature, Nature, vol. 522(7555), pages 162-163, June.
    • Handle: RePEc:nat:nature:v:522:y:2015:i:7555:d:10.1038_nature14528
    DOI: 10.1038/nature14528
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    Cited by:

    1. Albert Stuart Reece & Gary Kenneth Hulse, 2022. "Cannabis- and Substance-Related Epidemiological Patterns of Chromosomal Congenital Anomalies in Europe: Geospatiotemporal and Causal Inferential Study," IJERPH, MDPI, vol. 19(18), pages 1-51, September.

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