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Genome-wide identification of zero nucleotide recursive splicing in Drosophila

Author

Listed:
  • Michael O. Duff

    (Institute for Systems Genomics, University of Connecticut Health Center)

  • Sara Olson

    (Institute for Systems Genomics, University of Connecticut Health Center)

  • Xintao Wei

    (Institute for Systems Genomics, University of Connecticut Health Center)

  • Sandra C. Garrett

    (Institute for Systems Genomics, University of Connecticut Health Center)

  • Ahmad Osman

    (Institute for Systems Genomics, University of Connecticut Health Center)

  • Mohan Bolisetty

    (Institute for Systems Genomics, University of Connecticut Health Center)

  • Alex Plocik

    (Institute for Systems Genomics, University of Connecticut Health Center)

  • Susan E. Celniker

    (Lawrence Berkeley National Laboratory)

  • Brenton R. Graveley

    (Institute for Systems Genomics, University of Connecticut Health Center)

Abstract

In flies, some introns contain internal splice sites that cause ‘recursive splicing’, a multi-step removal of a single intron; this study demonstrates that the scope of this regulatory mechanism is much more extensive in flies than had been appreciated, and provides details about the recursive splicing process.

Suggested Citation

  • Michael O. Duff & Sara Olson & Xintao Wei & Sandra C. Garrett & Ahmad Osman & Mohan Bolisetty & Alex Plocik & Susan E. Celniker & Brenton R. Graveley, 2015. "Genome-wide identification of zero nucleotide recursive splicing in Drosophila," Nature, Nature, vol. 521(7552), pages 376-379, May.
    • Handle: RePEc:nat:nature:v:521:y:2015:i:7552:d:10.1038_nature14475
    DOI: 10.1038/nature14475
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