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NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs

Author

Listed:
  • Hana Cahová

    (Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany)

  • Marie-Luise Winz

    (Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany)

  • Katharina Höfer

    (Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany)

  • Gabriele Nübel

    (Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany)

  • Andres Jäschke

    (Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120 Heidelberg, Germany)

Abstract

A newly developed method, NAD captureSeq, has been used to show that bacteria cap the 5′-ends of some RNAs to protect against degradation, much as happens with eukaryotic messenger RNAs, although with a different modification: nicotinamide adenine dinucleotide.

Suggested Citation

  • Hana Cahová & Marie-Luise Winz & Katharina Höfer & Gabriele Nübel & Andres Jäschke, 2015. "NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs," Nature, Nature, vol. 519(7543), pages 374-377, March.
    • Handle: RePEc:nat:nature:v:519:y:2015:i:7543:d:10.1038_nature14020
    DOI: 10.1038/nature14020
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    Cited by:

    1. Sunny Sharma & Jun Yang & Ewa Grudzien-Nogalska & Jessica Shivas & Kelvin Y. Kwan & Megerditch Kiledjian, 2022. "Xrn1 is a deNADding enzyme modulating mitochondrial NAD-capped RNA," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    2. José Vicente Gomes-Filho & Ruth Breuer & Hector Gabriel Morales-Filloy & Nadiia Pozhydaieva & Andreas Borst & Nicole Paczia & Jörg Soppa & Katharina Höfer & Andres Jäschke & Lennart Randau, 2023. "Identification of NAD-RNA species and ADPR-RNA decapping in Archaea," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

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