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CRISPR engineering turns on genes

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  • Seung Woo Cho

    (Seung Woo Cho and Howard Y. Chang are in the Program in Epithelial Biology and the Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA.)

  • Howard Y. Chang

    (Seung Woo Cho and Howard Y. Chang are in the Program in Epithelial Biology and the Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA.)

Abstract

The repurposing of a bacterial defence system known as CRISPR into a potent activator of gene expression in human cells enables powerful studies of gene function, as exemplified in cancer cells. See Article p.583

Suggested Citation

  • Seung Woo Cho & Howard Y. Chang, 2015. "CRISPR engineering turns on genes," Nature, Nature, vol. 517(7536), pages 560-562, January.
    • Handle: RePEc:nat:nature:v:517:y:2015:i:7536:d:10.1038_517560a
    DOI: 10.1038/517560a
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