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Identification of multipotent mammary stem cells by protein C receptor expression

Author

Listed:
  • Daisong Wang

    (The State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences)

  • Cheguo Cai

    (The State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences)

  • Xiaobing Dong

    (The State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences)

  • Qing Cissy Yu

    (The State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences)

  • Xiao-Ou Zhang

    (Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences)

  • Li Yang

    (Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences)

  • Yi Arial Zeng

    (The State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences)

Abstract

Using transplantation and lineage-tracing strategies, protein C receptor is identified as a marker of mammary stem cells in mice, with potential implications for understanding the initiation of breast cancer.

Suggested Citation

  • Daisong Wang & Cheguo Cai & Xiaobing Dong & Qing Cissy Yu & Xiao-Ou Zhang & Li Yang & Yi Arial Zeng, 2015. "Identification of multipotent mammary stem cells by protein C receptor expression," Nature, Nature, vol. 517(7532), pages 81-84, January.
    • Handle: RePEc:nat:nature:v:517:y:2015:i:7532:d:10.1038_nature13851
    DOI: 10.1038/nature13851
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    Cited by:

    1. Maša Alečković & Simona Cristea & Carlos R. Gil Del Alcazar & Pengze Yan & Lina Ding & Ethan D. Krop & Nicholas W. Harper & Ernesto Rojas Jimenez & Donghao Lu & Anushree C. Gulvady & Pierre Foidart & , 2022. "Breast cancer prevention by short-term inhibition of TGFβ signaling," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    2. Elena Spina & Julia Simundza & Angela Incassati & Anupama Chandramouli & Matthias C. Kugler & Ziyan Lin & Alireza Khodadadi-Jamayran & Christine J. Watson & Pamela Cowin, 2022. "Gpr125 is a unifying hallmark of multiple mammary progenitors coupled to tumor latency," Nature Communications, Nature, vol. 13(1), pages 1-17, December.

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