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A cross-chiral RNA polymerase ribozyme

Author

Listed:
  • Jonathan T. Sczepanski

    (The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA)

  • Gerald F. Joyce

    (The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA)

Abstract

Here, a cross-chiral RNA polymerase is developed—an RNA enzyme that can catalyse the templated polymerization of activated mononucleotides that are of the opposite handedness—shedding light on how RNA-based life could have emerged.

Suggested Citation

  • Jonathan T. Sczepanski & Gerald F. Joyce, 2014. "A cross-chiral RNA polymerase ribozyme," Nature, Nature, vol. 515(7527), pages 440-442, November.
  • Handle: RePEc:nat:nature:v:515:y:2014:i:7527:d:10.1038_nature13900
    DOI: 10.1038/nature13900
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    Cited by:

    1. Tony Z. Jia & Yutetsu Kuruma, 2019. "Recent Advances in Origins of Life Research by Biophysicists in Japan," Challenges, MDPI, vol. 10(1), pages 1-21, April.

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