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The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function

Author

Listed:
  • Diogo Fonseca-Pereira

    (Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Avenida Professor Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal)

  • Sílvia Arroz-Madeira

    (Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Avenida Professor Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal)

  • Mariana Rodrigues-Campos

    (Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Avenida Professor Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal)

  • Inês A. M. Barbosa

    (Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Avenida Professor Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal)

  • Rita G. Domingues

    (Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Avenida Professor Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal)

  • Teresa Bento

    (Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Avenida Professor Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal)

  • Afonso R. M. Almeida

    (Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Avenida Professor Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal)

  • Hélder Ribeiro

    (Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Avenida Professor Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal)

  • Alexandre J. Potocnik

    (MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Institute of Immunology and Infection Research, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK)

  • Hideki Enomoto

    (Laboratory for Neuronal Differentiation and Regeneration, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
    Graduate School of Medicine, Kobe University7-5-1 Kusunoki-cho, Chuo-ku, Kobe City, Hyogo 650-0017, Japan)

  • Henrique Veiga-Fernandes

    (Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Avenida Professor Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal)

Abstract

Haematopoietic stem cells are direct targets for neurotrophic factors, indicating that haematopoietic stem cells and neurons are regulated by similar signals.

Suggested Citation

  • Diogo Fonseca-Pereira & Sílvia Arroz-Madeira & Mariana Rodrigues-Campos & Inês A. M. Barbosa & Rita G. Domingues & Teresa Bento & Afonso R. M. Almeida & Hélder Ribeiro & Alexandre J. Potocnik & Hideki, 2014. "The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function," Nature, Nature, vol. 514(7520), pages 98-101, October.
    • Handle: RePEc:nat:nature:v:514:y:2014:i:7520:d:10.1038_nature13498
    DOI: 10.1038/nature13498
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