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Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation

Author

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  • Yoshiki Omatsu

    (Institute for Frontier Medical Sciences, Kyoto University
    Japan Science and Technology Agency (JST), Core Research for Evolutional Science and Technology (CREST), 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan)

  • Masanari Seike

    (Institute for Frontier Medical Sciences, Kyoto University
    Japan Science and Technology Agency (JST), Core Research for Evolutional Science and Technology (CREST), 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan)

  • Tatsuki Sugiyama

    (Institute for Frontier Medical Sciences, Kyoto University
    Japan Science and Technology Agency (JST), Core Research for Evolutional Science and Technology (CREST), 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan)

  • Tsutomu Kume

    (Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University)

  • Takashi Nagasawa

    (Institute for Frontier Medical Sciences, Kyoto University
    Japan Science and Technology Agency (JST), Core Research for Evolutional Science and Technology (CREST), 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan)

Abstract

Transcription factor Foxc1 is a key regulator of haematopoietic stem/progenitor cell niche formation.

Suggested Citation

  • Yoshiki Omatsu & Masanari Seike & Tatsuki Sugiyama & Tsutomu Kume & Takashi Nagasawa, 2014. "Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation," Nature, Nature, vol. 508(7497), pages 536-540, April.
  • Handle: RePEc:nat:nature:v:508:y:2014:i:7497:d:10.1038_nature13071
    DOI: 10.1038/nature13071
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    Citations

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    Cited by:

    1. Trent D. Hall & Hyunjin Kim & Mahmoud Dabbah & Jacquelyn A. Myers & Jeremy Chase Crawford & Antonio Morales-Hernandez & Claire E. Caprio & Pramika Sriram & Emilia Kooienga & Marta Derecka & Esther A. , 2022. "Murine fetal bone marrow does not support functional hematopoietic stem and progenitor cells until birth," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    2. Yoshiki Omatsu & Shota Aiba & Tomonori Maeta & Kei Higaki & Kazunari Aoki & Hitomi Watanabe & Gen Kondoh & Riko Nishimura & Shu Takeda & Ung-il Chung & Takashi Nagasawa, 2022. "Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
    3. Taichi Nakatani & Tatsuki Sugiyama & Yoshiki Omatsu & Hitomi Watanabe & Gen Kondoh & Takashi Nagasawa, 2023. "Ebf3+ niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

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