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miRNAs trigger widespread epigenetically activated siRNAs from transposons in Arabidopsis

Author

Listed:
  • Kate M. Creasey

    (Cold Spring Harbor Laboratory, 1 Bungtown Road)

  • Jixian Zhai

    (15 Innovation Way, University of Delaware)

  • Filipe Borges

    (Cold Spring Harbor Laboratory, 1 Bungtown Road)

  • Frederic Van Ex

    (Cold Spring Harbor Laboratory, 1 Bungtown Road)

  • Michael Regulski

    (Cold Spring Harbor Laboratory, 1 Bungtown Road)

  • Blake C. Meyers

    (15 Innovation Way, University of Delaware)

  • Robert A. Martienssen

    (Cold Spring Harbor Laboratory, 1 Bungtown Road
    Howard Hughes Medical Institute-Gordon and Betty Moore Foundation
    Chaire Blaise Pascal, Institut de Biologie de l’Ecole Normale Supérieure (IBENS), 75230 Paris, France)

Abstract

The generation of widespread epigenetically activated short interfering RNAs by the targeting of microRNAs to transposon transcripts in Arabidopsis thaliana is shown to be a latent mechanism that only becomes active when the transcripts are epigenetically reactivated, for example, during reprogramming of the germ line.

Suggested Citation

  • Kate M. Creasey & Jixian Zhai & Filipe Borges & Frederic Van Ex & Michael Regulski & Blake C. Meyers & Robert A. Martienssen, 2014. "miRNAs trigger widespread epigenetically activated siRNAs from transposons in Arabidopsis," Nature, Nature, vol. 508(7496), pages 411-415, April.
  • Handle: RePEc:nat:nature:v:508:y:2014:i:7496:d:10.1038_nature13069
    DOI: 10.1038/nature13069
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