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Retraction Note: The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

Author

Listed:
  • Nisha Narayan
  • In Hye Lee
  • Ronen Borenstein
  • Junhui Sun
  • Renee Wong
  • Guang Tong
  • Maria M. Fergusson
  • Jie Liu
  • Ilsa I. Rovira
  • Hwei-Ling Cheng
  • Guanghui Wang
  • Marjan Gucek
  • David Lombard
  • Fredrick W. Alt
  • Michael N. Sack
  • Elizabeth Murphy
  • Liu Cao
  • Toren Finkel

Abstract

We retract this Article because some of the data, specifically the data reported in Fig. 2 demonstrating an in vitro requirement for Sirt2 in TNF-α-mediated necroptosis, appears to be irreproducible. We and others have confirmed that Sirt2 and RIP3interact, and we continue to believe that the absence of Sirt2 protects against ischaemic myocardial damage.

Suggested Citation

  • Nisha Narayan & In Hye Lee & Ronen Borenstein & Junhui Sun & Renee Wong & Guang Tong & Maria M. Fergusson & Jie Liu & Ilsa I. Rovira & Hwei-Ling Cheng & Guanghui Wang & Marjan Gucek & David Lombard & , 2014. "Retraction Note: The NAD-dependent deacetylase SIRT2 is required for programmed necrosis," Nature, Nature, vol. 506(7489), pages 516-516, February.
  • Handle: RePEc:nat:nature:v:506:y:2014:i:7489:d:10.1038_nature12897
    DOI: 10.1038/nature12897
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