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A new metabolic cell-wall labelling method reveals peptidoglycan in Chlamydia trachomatis

Author

Listed:
  • G. W. Liechti

    (F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, Maryland 20814-4799, USA)

  • E. Kuru

    (Interdisciplinary Biochemistry Program, Indiana University)

  • E. Hall

    (Indiana University)

  • A. Kalinda

    (Indiana University)

  • Y. V. Brun

    (Indiana University)

  • M. VanNieuwenhze

    (Indiana University)

  • A. T. Maurelli

    (F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, Maryland 20814-4799, USA)

Abstract

Peptidoglycan is an essential structural component of the cell wall in the majority of bacteria, but the obligate intracellular human pathogen Chlamydia trachomatis was thought to be one of the few exceptions; here a click chemistry approach is used to label peptidoglycan in replicating C. trachomatis with novel d-amino acid dipeptide probes.

Suggested Citation

  • G. W. Liechti & E. Kuru & E. Hall & A. Kalinda & Y. V. Brun & M. VanNieuwenhze & A. T. Maurelli, 2014. "A new metabolic cell-wall labelling method reveals peptidoglycan in Chlamydia trachomatis," Nature, Nature, vol. 506(7489), pages 507-510, February.
  • Handle: RePEc:nat:nature:v:506:y:2014:i:7489:d:10.1038_nature12892
    DOI: 10.1038/nature12892
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    Cited by:

    1. Elena Rivas-Marin & David Moyano-Palazuelo & Valentina Henriques & Enrique Merino & Damien P. Devos, 2023. "Essential gene complement of Planctopirus limnophila from the bacterial phylum Planctomycetes," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

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