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RETRACTED ARTICLE: Bidirectional developmental potential in reprogrammed cells with acquired pluripotency

Author

Listed:
  • Haruko Obokata

    (Laboratory for Cellular Reprogramming, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
    Laboratory for Genomic Reprogramming, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
    Laboratory for Tissue Engineering and Regenerative Medicine, Brigham and Women’s Hospital, Harvard Medical School)

  • Yoshiki Sasai

    (Laboratory for Organogenesis and Neurogenesis, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan)

  • Hitoshi Niwa

    (Laboratory for Pluripotent Stem Cell Studies, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan)

  • Mitsutaka Kadota

    (Genome Resource and Analysis Unit, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan)

  • Munazah Andrabi

    (Genome Resource and Analysis Unit, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan)

  • Nozomu Takata

    (Laboratory for Organogenesis and Neurogenesis, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan)

  • Mikiko Tokoro

    (Laboratory for Genomic Reprogramming, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan)

  • Yukari Terashita

    (Laboratory for Cellular Reprogramming, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
    Laboratory for Genomic Reprogramming, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan)

  • Shigenobu Yonemura

    (Electron Microscopy Laboratory, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan)

  • Charles A. Vacanti

    (Laboratory for Tissue Engineering and Regenerative Medicine, Brigham and Women’s Hospital, Harvard Medical School)

  • Teruhiko Wakayama

    (Laboratory for Genomic Reprogramming, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan
    Faculty of Life and Environmental Sciences, University of Yamanashi, Yamanashi 400-8510, Japan)

Abstract

One of two papers describing a reprogramming phenomenon called stimulus-triggered acquisition of pluripotency (STAP) — in STAP, lineage-committed adult somatic cells are reprogrammed to pluripotency by transient exposure to low-pH treatment, and extensive analysis of the molecular features and developmental potential of STAP cells indicates that they represent a unique state of pluripotency.

Suggested Citation

  • Haruko Obokata & Yoshiki Sasai & Hitoshi Niwa & Mitsutaka Kadota & Munazah Andrabi & Nozomu Takata & Mikiko Tokoro & Yukari Terashita & Shigenobu Yonemura & Charles A. Vacanti & Teruhiko Wakayama, 2014. "RETRACTED ARTICLE: Bidirectional developmental potential in reprogrammed cells with acquired pluripotency," Nature, Nature, vol. 505(7485), pages 676-680, January.
    • Handle: RePEc:nat:nature:v:505:y:2014:i:7485:d:10.1038_nature12969
    DOI: 10.1038/nature12969
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